Evidence map›Paper›PMID 30753250›Full record

Observational studyAge and ageing2019

Changes in physical and mental health are associated with cardiovascular disease incidence in postmenopausal women.

Nazmus Saquib, Robert Brunner, Manisha Desai, Candyce Kroenke, Lisa W Martin, Martha Daviglus, Norrina B Allen, Jennifer Robinson, Hilary Tindle, Marcia L Stefanick

Abstract readObservational Study
In one paragraph

Observational study in Age and ageing, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. The Association of Neighborhood Changes with Health-Related Quality of Life in the Women's Health Initiative.International journal of environmental research and public health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nazmus SaquibCollege of Medicine, Sulaiman Al-Rajhi Colleges, Al-Qassim, Saudi Arabia.
Robert BrunnerUniversity of Nevada, Reno, USA.
Manisha DesaiDepartment of Medicine, School of Medicine, Stanford University, Stanford, USA.
Candyce KroenkeKaiser Permanente, Oakland, USA.
Lisa W MartinGeorge Washington University, Washington, USA.
Martha DaviglusNorthwestern University, Chicago, USA.
Norrina B AllenNorthwestern University, Chicago, USA.
Jennifer RobinsonThe University of Iowa, Iowa City, USA.
Hilary TindleUniversity of Pittsburgh, Pittsburgh, USA.
Marcia L StefanickDepartment of Medicine, School of Medicine, Stanford University, Stanford, USA.

Funding

Social networks, breast cancer treatment, and survivalK07CA187403 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI KROENKE, CANDYCE H · 2015 to 2019
$914k
NCI NIH HHS K07 CA187403
6 · The paper itself

Abstract

backgroundphysical and mental health are important risk factors for cardiovascular disease (CVD) incidence and death among postmenopausal women. The objective of this study was to assess whether changes in physical and mental health were associated with CVD incidence and death.

methodsin the Women's Health Initiative Observational Study, 48,906 women (50-79 years) had complete data at baseline on physical and mental health (assessed with Short Form-36) and key covariates. Changes in self-reported physical and mental health were calculated between baseline and year 3. Incident CVD and death between year 3 and end of the study were verified with medical records.

resultsover a median 8.2-year follow-up, 2,319 women developed CVD, and 1,571 women died, including 361 CVD deaths. Women with continued poor health and those with worsened health had significantly increased risk of CVD incidence, CVD-specific death and all-cause death relative to women with continued good health. Both major and minor declines in physical health were associated with an increased risk of these outcomes relative to women with no change in physical health. Only major declines in mental health were associated with poor prognosis.

conclusionschanges in physical and mental health over 3 years were independently associated with subsequent CVD events.

Indexed as

PostmenopauseAgedCardiovascular DiseasesFemaleHealth StatusHumansIncidenceMental HealthMiddle AgedRisk FactorsSurveys and Questionnairesall-cause mortalitycardiovascular diseasehealth-related quality of lifeolder peoplephysical healthwomen

Identifiers

PMID30753250
PMCPMC8453231

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.