Evidence map›Paper›PMID 30753114›Full record

ArticleAmerican journal of physiology. Endocrinology and metabolism2019

Skeletal muscle fiber type-selective effects of acute exercise on insulin-stimulated glucose uptake in insulin-resistant, high-fat-fed rats.

Mark W Pataky, Carmen S Yu, Yilin Nie, Edward B Arias, Manak Singh, Christopher L Mendias, Robert J Ploutz-Snyder, Gregory D Cartee

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Endocrinology and metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mark W PatakyMuscle Biology Laboratory, School of Kinesiology, University of Michigan , Ann Arbor, Michigan.
Carmen S YuMuscle Biology Laboratory, School of Kinesiology, University of Michigan , Ann Arbor, Michigan.
Yilin NieMuscle Biology Laboratory, School of Kinesiology, University of Michigan , Ann Arbor, Michigan.
Edward B AriasMuscle Biology Laboratory, School of Kinesiology, University of Michigan , Ann Arbor, Michigan.
Manak SinghMuscle Biology Laboratory, School of Kinesiology, University of Michigan , Ann Arbor, Michigan.
Christopher L MendiasHospital for Special Surgery and Department of Physiology and Biophysics, Weill Cornell Medical College , New York, New York.ORCID 0000-0002-2384-0171
Robert J Ploutz-SnyderApplied Biostatistics Laboratory, University of Michigan , Ann Arbor, Michigan.
Gregory D CarteeMuscle Biology Laboratory, School of Kinesiology, University of Michigan , Ann Arbor, Michigan.
University of Michigan · USHospital for Special Surgery · US

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DAVID P OLSON · 2013 to 2026
$24.3M
Skeletal Muscle Glucose Uptake: Exercise and InsulinR01DK071771 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CARTEE, GREGORY D. · 2006 to 2020
$4.5M
NIDDK NIH HHS P30 DK020572NIDDK NIH HHS R01 DK071771
6 · The paper itself

Abstract

Insulin-stimulated glucose uptake (GU) by skeletal muscle is enhanced several hours after acute exercise in rats with normal or reduced insulin sensitivity. Skeletal muscle is composed of multiple fiber types, but exercise's effect on fiber type-specific insulin-stimulated GU in insulin-resistant muscle was previously unknown. Male rats were fed a high-fat diet (HFD; 2 wk) and were either sedentary (SED) or exercised (2-h exercise). Other, low-fat diet-fed (LFD) rats remained SED. Rats were studied immediately postexercise (IPEX) or 3 h postexercise (3hPEX). Epitrochlearis muscles from IPEX rats were incubated in 2-deoxy-[

Indexed as

Insulin ResistanceAnimalsDiet, High-FatGlucoseGlucose Transporter Type 4GlycogenInsulinLipid DropletsMaleMuscle Fibers, Fast-TwitchMuscle Fibers, SkeletalMuscle Fibers, Slow-TwitchMuscle, SkeletalPhysical Conditioning, AnimalRatsRats, WistarGlucoseGlucose Transporter Type 4GlycogenInsulinSlc2a4 protein, ratglucose transportGLUT4insulin sensitivityintramuscular triglycerideslipid droplet

Identifiers

PMID30753114
PMCPMC6580167
OpenAlexW2913884155

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.