Evidence map›Paper›PMID 30747710›Full record

ArticleeLife2019

Regional complexity in enteric neuron wiring reflects diversity of motility patterns in the mouse large intestine.

Zhiling Li, Marlene M Hao, Chris Van den Haute, Veerle Baekelandt, Werend Boesmans, Pieter Vanden Berghe

Abstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed.

  1. Article
  2. Time-resolved morphological and transcriptomic characterization of early enteric neuron subtype emergence in chick.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Intestinal muscularis in health and disease.Communications biology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Whole-Gut Spatial Genomic Analysis Reveals Molecular Regionalization of the Differentiating Zebrafish Enteric Nervous System.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Unique properties of proximal and distal colon reflect distinct motor functions.American journal of physiology. Gastrointestinal and liver physiology · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhiling LiLaboratory for Enteric NeuroScience (LENS), Translational Research Center for Gastrointestinal Disorders (TARGID), University of Leuven, Leuven, Belgium.ORCID 0000-0002-3888-971X
Marlene M HaoDepartment of Anatomy and Neuroscience, University of Melbourne, Melbourne, Australia.ORCID 0000-0002-9701-8252
Chris Van den HauteLaboratory for Neurobiology and Gene Therapy, Department of Neurosciences, KU Leuven, Leuven, Belgium.
Veerle BaekelandtLaboratory for Neurobiology and Gene Therapy, Department of Neurosciences, KU Leuven, Leuven, Belgium.ORCID 0000-0001-8966-2921
Werend BoesmansLaboratory for Enteric NeuroScience (LENS), Translational Research Center for Gastrointestinal Disorders (TARGID), University of Leuven, Leuven, Belgium.ORCID 0000-0002-2426-0451
Pieter Vanden BergheLaboratory for Enteric NeuroScience (LENS), Translational Research Center for Gastrointestinal Disorders (TARGID), University of Leuven, Leuven, Belgium.ORCID 0000-0002-0009-2094

Funding

Belgian National Fund for Scientific Research G.0921.15 SBO/S006617NChinese Scholarship Council 201408370078Fonds Wetenschappelijk Onderzoek 12G1214NFonds Wetenschappelijk Onderzoek G.0921.15Fonds Wetenschappelijk Onderzoek SBO/S006617NFund for Scientific Research Flanders G.0921.15 SBO/S006617NHercules Foundation AKUL/11/37Hercules Foundation AKUL/13/37Hercules Foundation AKUL/15/37Instituut voor Innovatie door Wetenschap en Technologie SBO/130065IWT SBO/130065KU Leuven C32/15/031KULeuven C32/15/031National Health and Medical Research Council APP1655567
6 · The paper itself

Abstract

The enteric nervous system controls a variety of gastrointestinal functions including intestinal motility. The minimal neuronal circuit necessary to direct peristalsis is well-characterized but several intestinal regions display also other motility patterns for which the underlying circuits and connectivity schemes that coordinate the transition between those patterns are poorly understood. We investigated whether in regions with a richer palette of motility patterns, the underlying nerve circuits reflect this complexity. Using Ca

Indexed as

Gastrointestinal MotilityAnimalsIntestine, LargeMiceNerve NetNeuronsOptical Imagingcalcium imagingenteric nervous systemintestinemotilitymouseneural tracingneurocircuitryneuroscience

Identifiers

PMID30747710
PMCPMC6391068

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.