Evidence map›Paper›PMID 30747306›Full record

ReviewCurrent hypertension reports2019

Personalized Medicine and the Treatment of Hypertension.

Sarah Melville, James Brian Byrd

Abstract readReview
In one paragraph

Review in Current hypertension reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Personalized Medicine in Kidney Disease.Journal of personalized medicine · 2023
    Article
  9. Observational
  10. Personalized hypertension treatment recommendations by a data-driven model.BMC medical informatics and decision making · 2023
    Article
  11. Review
  12. Article
  13. Clinical Network for Big Data and Personalized Health: Study Protocol and Preliminary Results.International journal of environmental research and public health · 2022
    Article
  14. Review
  15. Review
  16. Article
  17. Connected Health in Hypertension Management.Frontiers in cardiovascular medicine · 2019
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sarah MelvilleCardioVascular Research New Brunswick, Saint John Regional Hospital, HHN, Saint John, Canada.
James Brian ByrdDepartment of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan Medical School, 5570C MSRB II, 1150 West Medical Center Drive, SPC 5678, Ann Arbor, MI, 48109-5678, USA. jbbyrd@med.umich.edu.

Funding

A Novel Biomarker of Mineralocorticoid Receptor ActivationK23HL128909 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BYRD, JAMES BRIAN · 2016 to 2020
$972k
NHLBI NIH HHS K23 HL128909
6 · The paper itself

Abstract

purpose of reviewThe purpose of this review is to discuss the implications of personalized medicine for the treatment of hypertension, including resistant hypertension. RECENT

findingsWe suggest a framework for the personalized treatment of hypertension based on the concept of a trade-off between simplicity and personalization. This framework is based on treatment strategies classified as low, medium, or high information burden personalization approaches. The extent to which a higher information burden is justified depends on the clinical scenario, particularly the ease with which the blood pressure can be controlled. A one-size-fits-many treatment strategy for hypertension is efficacious for most people; however, a more personalized approach could be useful in patients with subtypes of hypertension that do not respond as expected to treatment. Clinicians seeing patients with unusual hypertension phenotypes should be familiar with emerging trends in personalized treatment of hypertension.

Indexed as

Antihypertensive AgentsHypertensionPrecision MedicineBlood PressureHumansPhenotypeAntihypertensive AgentsBlood pressureHypertensionPersonalized medicinePopulation healthPrimary aldosteronismResistant hypertension

Identifiers

PMID30747306
PMCPMC6594382

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.