Evidence map›Paper›PMID 30747295›Full record

ArticleParasitology research2019

5-HT

Jefferson Alvim de Oliveira, Michelle A R Freitas, Enio Chaves de Oliveira, Samir Jabari, Axel Brehmer, Alexandre Barcelos Morais da Silveira

Abstract read
PubMed Publisher
In one paragraph

Article in Parasitology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Disorders of the enteric nervous system - a holistic view.Nature reviews. Gastroenterology & hepatology · 2021
    Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Jefferson Alvim de OliveiraHuman Anatomy Sector, Neurosciences Laboratory, ICBIM, Campus Umuarama, Universidade Federal de Uberlândia, Uberlândia, Minas Gerais, 38400-902, Brazil.
Michelle A R FreitasParasitology Sector, ICBIM, Universidade Federal de Uberlândia, Uberlândia, Minas Gerais, 38400-902, Brazil.
Enio Chaves de OliveiraDepartment of Surgery, Medical School, Universidade Federal de Goiás, Goiânia, 74605-020, Brazil.
Samir JabariInstitute of Anatomy I, University of Erlangen-Nuremberg, Krankenhausstr. 9, 91054, Erlangen, Germany.
Axel BrehmerInstitute of Anatomy I, University of Erlangen-Nuremberg, Krankenhausstr. 9, 91054, Erlangen, Germany.
Alexandre Barcelos Morais da SilveiraHuman Anatomy Sector, Neurosciences Laboratory, ICBIM, Campus Umuarama, Universidade Federal de Uberlândia, Uberlândia, Minas Gerais, 38400-902, Brazil. alec@ufu.br.
Universidade Federal de Uberlândia · BRFriedrich-Alexander-Universität Erlangen-Nürnberg · DEUniversidade Federal de Goiás · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chagas disease is caused by Trypanosoma cruzi and remains one of the most neglected diseases in Latin America. One of its clinical forms is Chagas megacolon. Despite being known for more than half a century, detailed causes are still obscure. Recent evidence indicates a close relationship between the immune system and the enteric nervous system in the etiology of chagasic megacolon pathology. It is believed that low expression of the 5-HT

Indexed as

Antigens, CD20CD4 AntigensCD8 AntigensChagas DiseaseEnteric Nervous SystemHumansImmune SystemLymphocytesMegacolonMiddle AgedReceptors, Serotonin, 5-HT3SerotoninTrypanosoma cruziAntigens, CD20CD4 AntigensCD8 AntigensHTR3E protein, humanReceptors, Serotonin, 5-HT3Serotonin5-HT3AChagas diseaseEnteric nervous systemLymphocytesMegacolon

Identifiers

PMID30747295
OpenAlexW2912653988

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.