SynthesisLangenbeck's archives of surgery2019
The influence of diverting loop ileostomy vs. colostomy on postoperative morbidity in restorative anterior resection for rectal cancer: a systematic review and meta-analysis.
Synthesis in Langenbeck's archives of surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 47 citations in OpenAlex.
- Early postoperative complications after transverse colostomy closure, a retrospective study.World journal of gastrointestinal surgery · 2024Trial
- Oral rehydration solution for the management of fluid and electrolyte disturbances in patients with an ileostomy: A scoping review.JPEN. Journal of parenteral and enteral nutrition · 2026Article
- A novel technique for the construction of an end ileostomy to prevent stoma outlet obstruction after rectal resection and total colectomy: a single-center retrospective study.Surgery today · 2025Article
- Protective loop ileostomy or colostomy? A risk evaluation of all common complications.Annals of coloproctology · 2024Article
- Analysis of the correlation between defunctioning stoma and postoperative low anterior resection syndrome in rectal cancer: a prospective cohort study.BMC gastroenterology · 2024Article
- Predictors for temporary stomas non-closure among non-metastatic rectal cancer patients undergoing curative resection: a retrospective analysis.World journal of surgical oncology · 2024Article
- Prophylactic defunctioning stomas improve clinical outcomes of anastomotic leak following rectal cancer resections: An analysis of the US Rectal Cancer Consortium.International journal of colorectal disease · 2024Article
- Efficacy of laparoscopic surgery for loop colostomy: a propensity-score-matched analysis.Techniques in coloproctology · 2023Article
- Short-Term Outcomes in Patients Undergoing Virtual/Ghost Ileostomy or Defunctioning Ileostomy after Anterior Resection of the Rectum: A Meta-Analysis.Journal of clinical medicine · 2023Review
- Temporary loop ileostomy versus transverse colostomy for laparoscopic colorectal surgery: a retrospective study.Surgery today · 2023Article
- A comparative study of stoma-related complications from diverting loop ileostomy or colostomy after colorectal surgery.Langenbeck's archives of surgery · 2023Article
- Risk factors for developing high-output ileostomy in CRC patients: a retrospective study.BMC surgery · 2021Article
- Low preoperative maximum squeezing pressure evaluated by anorectal manometry is a risk factor for non-reversal of diverting stoma.Langenbeck's archives of surgery · 2021Article
- The association of age with decline in renal function after low anterior resection and loop ileostomy for rectal cancer: a retrospective cohort prognostic factor study.BMC geriatrics · 2021Article
- The effect of online training-based continuous nursing care for rectal cancer-patients undergoing permanent colostomy.American journal of translational research · 2021Article
- Loop ileostomy versus loop colostomy as temporary deviation after anterior resection for rectal cancer.Langenbeck's archives of surgery · 2020Article
- How to Prevent Anastomotic Leak in Colorectal Surgery? A Systematic Review.Annals of coloproctology · 2020Review
- Hernia at the stoma site after loop ileostomy reversal.International journal of colorectal disease · 2020Article
- Neoadjuvant radiotherapy for rectal cancer management.World journal of gastroenterology · 2019Review
- High-Output Stoma Leading to the Diagnosis of Antiphospholipid Syndrome.Case reports in gastroenterologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this systematic review and meta-analysis was to evaluate the morbidity of loop ileostomy (LI) and loop colostomy (LC) creation in restorative anterior resection for rectal cancer as well as the morbidity of their reversal.
methodsPubMed, EMBASE, MEDLINE via Ovid, and Cochrane Library were systematically searched for records published from 1980 to 2017 by three independent researchers. The primary endpoint was overall morbidity after stoma creation and reversal. Mantel-Haenszel odds ratio (OR) was used to compare categorical variables. Clinical significance was evaluated using numbers needed to treat (NNT).
resultsSix studies (two randomized controlled trials and four observational studies) totaling 1063 patients (666 LI and 397 LC) were included in the meta-analysis. Overall morbidity rate after both stoma creation and closure was 15.6% in LI vs. 20.4% in LC [OR(95%CI) = 0.67 (0.29, 1.58); p = 0.36] [NNT(95%CI) = 21 (> 10.4 to benefit, > 2430.2 to harm)]. Morbidity rate after stoma creation was both statistically and clinically significantly lower after LI [18.2% vs. 30.6%; OR(95%CI) = 0.42 (0.25, 0.70); p = 0.001; NNT(95%CI) = 9 (4.7, 29.3)]. Dehydration rate was 3.1% (8/259) in LI vs. 0% (0/168) in LC. The difference was not statistically or clinically significant [OR(95%CI) = 3.00 (0.74, 12.22); p = 0.13; NNT (95%CI) = 33 (19.2, 101.9)]. Ileus rates after stoma closure were significantly higher in LI as compared to LC [5.2% vs. 1.7%; OR(95%CI) = 2.65 (1.13, 6.18); p = 0.02].
conclusionsThis meta-analysis found no difference between LI and LC in overall morbidity after stoma creation and closure. Morbidity rates following the creation of LI were significantly decreased at the cost of a risk for dehydration.
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