Evidence map›Paper›PMID 30747032›Full record

ArticlePulmonary circulation

Pathophysiology, incidence, management, and consequences of cardiac arrhythmia in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.

Meghan M Cirulis, John J Ryan, Stephen L Archer

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Pulmonary circulation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04554160 (ArrhythmiaS in Pulmonary arterIal hypeRtEnsion and Right Heart Failure Assessed by Continuous Long-term Cardiac Monitoring), which is not on this map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04554160 unknown statusnot on this map

ArrhythmiaS in Pulmonary arterIal hypeRtEnsion and Right Heart Failure Assessed by Continuous Long-term Cardiac Monitoring

TypeobservationalSponsorRigshospitalet, DenmarkRan2018 to 2024Enrolled40ConditionsPulmonary Hypertension, Arrhythmias, Cardiac, Heart Rate Variability, Risk AssessmentArmsLoop recorder implantation, A smartwatch
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Sudden cardiac death in pulmonary arterial hypertension.International journal of cardiology. Congenital heart disease · 2024
    Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Comparison of QT dispersion before and after PDA device closure in pediatrics.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2022
    Article
  13. Article
  14. Review
  15. Critical Care Management of Decompensated Right Heart Failure in Pulmonary Arterial Hypertension Patients - An Ongoing Approach.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2021
    Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Right ventricular dysfunction and long-term risk of death.Cardiovascular diagnosis and therapy · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Meghan M Cirulis1 Division of Pulmonary Medicine, Department of Medicine, University of Utah, Salt Lake City, UT, USA.
John J Ryan2 Division of Cardiovascular Medicine, Department of Medicine, University of Utah, Salt Lake City, UT, USA.
Stephen L Archer3 Department of Medicine, Queen's University, Kingston, ON, Canada.
University of Utah · USQueen's University · CA

Funding

O2 sensing in the human and rabbit ductus arteriosus.R01HL071115 · NHLBI · UNIVERSITY OF CHICAGO · PI ARCHER, STEPHEN L · 2004 to 2015
$3.1M
Impaired mitochondrial fusion in pulmonary arterial hypertensionRC1HL099462 · NHLBI · UNIVERSITY OF CHICAGO · PI ARCHER, STEPHEN L · 2009 to 2010
$1.0M
NHLBI NIH HHS R01 HL071115NHLBI NIH HHS RC1 HL099462
6 · The paper itself

Abstract

Arrhythmias are increasingly recognized as serious, end-stage complications of pre-capillary pulmonary hypertension, including pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). Although arrhythmias contribute to symptoms, morbidity, in-hospital mortality, and possibly sudden death in PAH/CTEPH, there remains a paucity of epidemiologic, pathophysiologic, and outcome data to guide management of these patients. This review summarizes the most current evidence on the topic: from the molecular mechanisms driving arrhythmia in the hypertrophied or failing right heart, to the clinical aspects of epidemiology, diagnosis, and management.

Indexed as

atrial fibrillationatrial flutterprognosisright heart failuresudden deathsupraventricular atrial arrhythmiasurvival

Identifiers

PMID30747032
PMCPMC6410395
OpenAlexW2913856453

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.