ArticleKorean journal of ophthalmology : KJO2019
Association between Three Heavy Metals and Dry Eye Disease in Korean Adults: Results of the Korean National Health and Nutrition Examination Survey.
Article in Korean journal of ophthalmology : KJO, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 15 citations in OpenAlex.
- Mitochondrial Damage in Hemoglobinopathies: The Role of Cell-Free mtDNA as a Potential Biomarker.Biomedicines · 2026Article
- Quantification of Metal(loid)s in Lubricating Eye Drops Used in the Treatment of Dry Eye Disease.Molecules (Basel, Switzerland) · 2023Article
- Impact of Microplastics on the Ocular Surface.International journal of molecular sciences · 2023Review
- Associations between Biomarkers of Metal Exposure and Dry Eye Metrics in Shipyard Welders: A Cross-Sectional Study.International journal of environmental research and public health · 2022Article
- Health Problems Among Workers Who Recycle Electronic Waste in Southern Thailand.Osong public health and research perspectives · 2020Article
- Topical Application ofJournal of ophthalmology · 2019Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
purposeTo investigate the associations between blood heavy metal concentrations and dry eye disease using a Korean population-based survey.
methodsThis study included 23,376 participants >40 years of age who participated in the Korean National Health and Nutrition Examination Survey from 2010 to 2012. Blood concentrations of lead, cadmium, and mercury were measured in all participants. The associations between blood heavy metal concentrations and dry eye disease were assessed using multivariate logistic regression analyses.
resultsAfter adjusting for potential confounders, including age, sex, lifestyle behaviors and sociodemographic factors, the analyses revealed an increased odds ratio (OR) for dry eye disease with higher blood mercury concentrations (tertile 2: OR, 1.22; 95% confidence interval [CI], 0.91 to 1.64; tertile 3: OR, 1.39; 95% CI, 1.02 to 1.89;
conclusionsMercury concentrations in blood were associated with dry eye disease. Our results suggested that controlling environmental exposure to mercury may be necessary to reduce the incidence of dry eye disease.
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