ArticlemSystems
Unique Patterns and Biogeochemical Relevance of Two-Component Sensing in Marine Bacteria.
Article in mSystems. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Development of covalent inhibitors for bacterial histidine kinases.Chemical communications (Cambridge, England) · 2026Article
- Decoding the genetic drivers of marine bacterial blooms through comparative genomics.Microbiome · 2025Article
- Genomic insights into biosynthesis and adaptation in the bioactive marine bacterium Streptomyces albidoflavus VIP-1 from the Red Sea.BMC microbiology · 2025Article
- Microbial sensor variation across biogeochemical conditions in the terrestrial deep subsurface.mSystems · 2024Article
- Proteomics analysis reveals differential acclimation of coastal and oceanicFrontiers in microbiology · 2024Article
- A Reduction of Transcriptional Regulation in Aquatic Oligotrophic Microorganisms Enhances Fitness in Nutrient-Poor Environments.Microbiology and molecular biology reviews : MMBR · 2023Review
- Molecular mechanisms underlying iron and phosphorus co-limitation responses in the nitrogen-fixing cyanobacterium Crocosphaera.The ISME journal · 2022Article
- Article
- Response of CoastalFrontiers in microbiology · 2021Article
- Divergent Genomic Adaptations in the Microbiomes of Arctic Subzero Sea-Ice and Cryopeg Brines.Frontiers in microbiology · 2021Article
- Meta-omics Provides Insights into the Impact of Hydrocarbon Contamination on Microbial Mat Functioning.Microbial ecology · 2020Article
- Minimal cobalt metabolism in the marine cyanobacteriumProceedings of the National Academy of Sciences of the United States of America · 2020Article
- Characterization of the Fe metalloproteome of a ubiquitous marine heterotroph, Pseudoalteromonas (BB2-AT2): multiple bacterioferritin copies enable significant Fe storage.Metallomics : integrated biometal science · 2020Article
- Revegetation on abandoned salt ponds relieves the seasonal fluctuation of soil microbiomes.BMC genomics · 2019Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two-component sensory (TCS) systems link microbial physiology to the environment and thus may play key roles in biogeochemical cycles. In this study, we surveyed the TCS systems of 328 diverse marine bacterial species. We identified lifestyle traits such as copiotrophy and diazotrophy that are associated with larger numbers of TCS system genes within the genome. We compared marine bacterial species with 1,152 reference bacterial species from a variety of habitats and found evidence of extra response regulators in marine genomes. Examining the location of TCS genes along the circular bacterial genome, we also found that marine bacteria have a large number of "orphan" genes, as well as many hybrid histidine kinases. The prevalence of "extra" response regulators, orphan genes, and hybrid TCS systems suggests that marine bacteria break with traditional understanding of how TCS systems operate. These trends suggest prevalent regulatory networking, which may allow coordinated physiological responses to multiple environmental signals and may represent a specific adaptation to the marine environment. We examine phylogenetic and lifestyle traits that influence the number and structure of two-component systems in the genome, finding, for example, that a lack of two-component systems is a hallmark of oligotrophy. Finally, in an effort to demonstrate the importance of TCS systems to marine biogeochemistry, we examined the distribution of
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