Evidence map›Paper›PMID 30746495›Full record

ArticlemSystems

Oxidative Pathways of Deoxyribose and Deoxyribonate Catabolism.

Morgan N Price, Jayashree Ray, Anthony T Iavarone, Hans K Carlson, Elizabeth M Ryan, Rex R Malmstrom, Adam P Arkin, Adam M Deutschbauer

Open access · goldAbstract read
In one paragraph

Article in mSystems. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
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  8. Article
  9. Review
  10. Biosynthesis and function of 7-deazaguanine derivatives in bacteria and phages.Microbiology and molecular biology reviews : MMBR · 2024
    Review
  11. Article
  12. Article
  13. Article
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  15. Article
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  18. Leveraging host metabolism for bisdemethoxycurcumin production inMetabolic engineering communications · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Morgan N PriceEnvironmental Genomics and Systems Biology, Lawrence Berkeley National Laboratory, Berkeley, California, USA.ORCID https://orcid.org/0000-0002-4251-0362
Jayashree RayEnvironmental Genomics and Systems Biology, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
Anthony T IavaroneQB3/Chemistry Mass Spectrometry Facility, University of California, Berkeley, California, USA.
Hans K CarlsonEnvironmental Genomics and Systems Biology, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
Elizabeth M RyanDOE Joint Genome Institute, Walnut Creek, California, USA.
Rex R MalmstromDOE Joint Genome Institute, Walnut Creek, California, USA.
Adam P ArkinEnvironmental Genomics and Systems Biology, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
Adam M DeutschbauerEnvironmental Genomics and Systems Biology, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
Lawrence Berkeley National Laboratory · USJoint Genome Institute · USUniversity of California, Berkeley · US

Funding

Pacific Biosciences PacBio RS Single Molecule Real Time SequencerS10OD018174 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI ROKHSAR, DANIEL SOLEYMAN · 2014 to 2014
$600k
High Definition Ion Mobility SpectrometerS10OD020062 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI WILLIAMS, EVAN R · 2015 to 2015
$590k
NIH HHS S10 OD018174NIH HHS S10 OD020062
6 · The paper itself

Abstract

Using genome-wide mutant fitness assays in diverse bacteria, we identified novel oxidative pathways for the catabolism of 2-deoxy-d-ribose and 2-deoxy-d-ribonate. We propose that deoxyribose is oxidized to deoxyribonate, oxidized to ketodeoxyribonate, and cleaved to acetyl coenzyme A (acetyl-CoA) and glyceryl-CoA. We have genetic evidence for this pathway in three genera of bacteria, and we confirmed the oxidation of deoxyribose to ketodeoxyribonate

Indexed as

deoxyribonate catabolismdeoxyribose catabolismhigh-throughput genetics

Identifiers

PMID30746495
PMCPMC6365646
OpenAlexW2766269329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.