ArticleScience advances2019
High-speed imaging of ice nucleation in water proves the existence of active sites.
Article in Science advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 175 citations in OpenAlex.
- Ice nucleation on microcline (001) in the absence of active sites.Nature communications · 2026Article
- Surface Structure of Polar Silver Iodide (0001) in Various Liquids: No Indication for a Surface Reconstruction.Chemphyschem : a European journal of chemical physics and physical chemistry · 2026Article
- Cryopreservation of Avian Erythrocytes Using Macromolecular Cryoprotectants.ACS polymers Au · 2026Article
- Chromatic forecasting hydrogels for anti-icing applications.Nature communications · 2025Article
- Passive Ice Protection Systems for Unmanned Aerial Vehicles Applications: A Review.Small (Weinheim an der Bergstrasse, Germany) · 2025Review
- Microfluidics for the biological analysis of atmospheric ice-nucleating particles: Perspectives and challenges.Biomicrofluidics · 2025Review
- Dynamic Fractal Ice Nano-Nucleators for Cancer Cryotherapy.Nano today · 2024Article
- High-speed cryo-microscopy reveals that ice-nucleating proteins ofScience advances · 2024Article
- How Water Binds to Microcline Feldspar (001).The journal of physical chemistry letters · 2024Article
- Universality of Hair as a Nucleant: Exploring the Effects of Surface Chemistry and Topography.Crystal growth & design · 2023Article
- Electron transparent nanotubes reveal crystallization pathways in confinement.Chemical science · 2023Article
- A highly active mineral-based ice nucleating agent supportsJournal of the Royal Society, Interface · 2023Article
- Poly(vinyl alcohol) Molecular Bottlebrushes Nucleate Ice.Biomacromolecules · 2022Article
- Electron microscopy and calorimetry of proteins in supercooled water.Scientific reports · 2022Article
- Accurate prediction of ice nucleation from room temperature water.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Direct measuring of single-heterogeneous bubble nucleation mediated by surface topology.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- The role of structural order in heterogeneous ice nucleation.Chemical science · 2022Article
- Volcanic ash ice nucleation activity is variably reduced by aging in water and sulfuric acid: the effects of leaching, dissolution, and precipitation.Environmental science: atmospheres · 2022Article
- Studying Ice with Environmental Scanning Electron Microscopy.Molecules (Basel, Switzerland) · 2021Review
- Sand-mediated ice seeding enables serum-free low-cryoprotectant cryopreservation of human induced pluripotent stem cells.Bioactive materials · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Understanding how surfaces direct nucleation is a complex problem that limits our ability to predict and control crystal formation. We here address this challenge using high-speed imaging to identify and quantify the sites at which ice nucleates in water droplets on the two natural cleavage faces of macroscopic feldspar substrates. Our data show that ice nucleation only occurs at a few locations, all of which are associated with micron-size surface pits. Similar behavior is observed on α-quartz substrates that lack cleavage planes. These results demonstrate that substrate heterogeneities are the salient factor in promoting nucleation and therefore prove the existence of active sites. We also provide strong evidence that the activity of these sites derives from a combination of surface chemistry and nanoscale topography. Our results have implications for the nucleation of many materials and suggest new strategies for promoting or inhibiting nucleation across a wide range of applications.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.