Evidence map›Paper›PMID 30746456›Full record

ArticleScience advances2019

Waterproof, electronics-enabled, epidermal microfluidic devices for sweat collection, biomarker analysis, and thermography in aquatic settings.

Jonathan T Reeder, Jungil Choi, Yeguang Xue, Philipp Gutruf, Justin Hanson, Mark Liu, Tyler Ray, Amay J Bandodkar, Raudel Avila, Wei Xia and 7 more

Abstract read
In one paragraph

Article in Science advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

89 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Photonic Nanomaterials for Wearable Health Solutions.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  12. Review
  13. Smart closed-loop drug delivery systems.Nature reviews bioengineering · 2025
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Jonathan T ReederDepartment of Materials Science and Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0002-7624-7355
Jungil ChoiDepartment of Materials Science and Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0002-3659-8978
Yeguang XueDepartment of Civil and Environmental Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0002-1968-5092
Philipp GutrufDepartment of Materials Science and Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0002-7183-7268
Justin HansonDepartment of Biological Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 USA.ORCID 0000-0002-5647-7954
Mark LiuDepartment of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0001-5152-3686
Tyler RayDepartment of Materials Science and Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0001-7047-9676
Amay J BandodkarDepartment of Materials Science and Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0002-1792-1506
Raudel AvilaDepartment of Civil and Environmental Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL 60208, USA.
Wei XiaDepartment of Civil and Environmental Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0002-5934-9026
Siddharth KrishnanDepartment of Materials Science and Engineering and Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0001-8032-7043
Shuai XuCenter for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA.
Kelly BarnesGatorade Sports Science Institute, 617 W. Main St., Barrington, IL 60010, USA.ORCID 0000-0003-4499-2753
Matthew PahnkeGatorade Sports Science Institute, 617 W. Main St., Barrington, IL 60010, USA.ORCID 0000-0002-4660-2918
Roozbeh GhaffariCenter for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA.
Yonggang HuangDepartment of Materials Science and Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0002-0483-8359
John A RogersDepartment of Materials Science and Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0002-3830-5980

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Noninvasive, in situ biochemical monitoring of physiological status, via the use of sweat, could enable new forms of health care diagnostics and personalized hydration strategies. Recent advances in sweat collection and sensing technologies offer powerful capabilities, but they are not effective for use in extreme situations such as aquatic or arid environments, because of unique challenges in eliminating interference/contamination from surrounding water, maintaining robust adhesion in the presence of viscous drag forces and/or vigorous motion, and preventing evaporation of collected sweat. This paper introduces materials and designs for waterproof, epidermal, microfluidic and electronic systems that adhere to the skin to enable capture, storage, and analysis of sweat, even while fully underwater. Field trials demonstrate the ability of these devices to collect quantitative in situ measurements of local sweat chloride concentration, local sweat loss (and sweat rate), and skin temperature during vigorous physical activity in controlled, indoor conditions and in open-ocean swimming.

Indexed as

Lab-On-A-Chip DevicesSeawaterWearable Electronic DevicesBiomarkersBiosensing TechniquesChloridesEpidermisEquipment DesignHumansMicrofluidicsSkinSweatSwimmingTemperatureThermographyBiomarkersChlorides

Identifiers

PMID30746456
PMCPMC6357724

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.