Evidence map›Paper›PMID 30746429›Full record

ArticleCurrent opinion in behavioral sciences2018

Addiction and Dopamine: Sex Differences and Insights from Studies of Smoking.

Nicole Petersen, Edythe D London

Abstract read
In one paragraph

Article in Current opinion in behavioral sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Interaction BetweenNeurology international · 2025
    Article
  3. Article
  4. Article
  5. Sex differences in dopamine release regulation in the striatum.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021
    Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nicole PetersenDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA, USA, 90024.
Edythe D LondonDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA, USA, 90024.

Funding

Transcranial Magnetic Stimulation and Tobacco Use Disorder: A Network-Level Approach with Attention to Sex as a Biological VariableR00DA045749 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PETERSEN, NICOLE · 2021 to 2023
$902k
Estrogen, dopamine D2-type receptors, and self-controlF32DA039715 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PETERSEN, NICOLE · 2015 to 2017
$113k
NIDA NIH HHS F32 DA039715NIDA NIH HHS R00 DA045749
6 · The paper itself

Abstract

Mesolimbic dopaminergic function influences addiction through effects on reinforcement learning, decision-making, and impulsivity. This review covers sex differences in dopaminergic neurochemistry, their hormonal and genetic determinants, and how differences in dopaminergic tone interact with sex and/or ovarian hormone status to affect cognitive functions. Findings from research on cigarette smoking reveal sex differences in striatal and midbrain dopamine D2-type receptor availability and striatal dopamine release that suggest mechanisms of nicotine dependence, and stronger subjective responses to nicotine and efficacy of nicotine replacement therapies in male smokers than in their female counterparts. Opportunities exist to extend such efforts in studies of how sex and hormone status influence other addictions.

Identifiers

PMID30746429
PMCPMC6368096

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.