ArticleWorld journal of clinical cases2019
Celiac crisis, a rare occurrence in adult celiac disease: A systematic review.
Article in World journal of clinical cases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- European Society for the Study of Coeliac Disease (ESsCD) 2025 Updated Guidelines on the Diagnosis and Management of Coeliac Disease in Adults. Part 2: Management, Follow-Up, and Complex Disease Courses.United European gastroenterology journal · 2026Guideline
- Celiac Crisis Complicated by Refeeding Syndrome: A Case Report and Pediatric-Adapted Diagnostic Criteria.Reports (MDPI) · 2026Article
- Comparative Effectiveness of Urine vs. Stool Gluten Immunogenic Peptides Testing for Monitoring Gluten Intake in Coeliac Patients: A Systematic Review and Meta-Analysis.Life (Basel, Switzerland) · 2025Review
- Celiac Crisis in the Postpartum: A Life-Threatening Cause of Diarrhea and Malnutrition.GE Portuguese journal of gastroenterology · 2025Article
- Celiac Crisis: A Rare Medical Emergency Case Report in Adult Celiac Disease.Case reports in gastrointestinal medicine · 2025Article
- Celiac Crisis: A Life-Threatening Complication of Celiac Disease.Middle East journal of digestive diseases · 2024Review
- A Clinical Case of a Celiac Crisis in an Adult With Type 1 Diabetes and Neurological Symptoms.Cureus · 2023Article
- Celiac crisis as the life-threatening onset of celiac disease in children: a case report.Frontiers in pediatrics · 2023Article
- Article
- The Gluten-Free Diet for Celiac Disease and Beyond.Nutrients · 2021Review
- A Japanese infant presenting with hypocalcemic seizures resulting from hypovitaminosis D induced by non-celiac gluten sensitivity.Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology · 2021Article
- Celiac Disease in an Adult Presenting as Behavioral Disturbances.The American journal of case reports · 2020Article
- Life-threatening onset of coeliac disease: a case report and literature review.BMJ open gastroenterology · 2020Review
- Hematologic Manifestations in Celiac Disease-A Practical Review.Medicina (Kaunas, Lithuania) · 2019Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCeliac crisis (CC), a potentially life-threatening condition, is one of the rare clinical presentations of celiac disease (CD). Several cases have been documented in the literature, mostly in children.
aimTo perform a review of CC cases reported in adult CD patients.
methodsA systematic search of the literature was conducted in two databases, PubMed/MEDLINE and EMBASE, using the term "celiac crisis" and its variant "coeliac crisis", from January 1970 onwards. Altogether, 29 articles reporting 42 biopsy-proven cases were found in the search. Here, we summarized the demographic, clinical characteristics, laboratory and diagnostic work-ups, and therapeutic management in these patients.
resultsAmong the 42 CD cases, the median age was 50 years (range 23-83), with a 2:1 female to male ratio. The majority of patients (88.1%) developed CC prior to CD diagnosis, while the remaining were previously diagnosed CD cases reporting low adherence to a gluten-free diet (GFD). Clinically, patients presented with severe diarrhea (all cases), weight loss (about two thirds) and, in particular situations, with neurologic (6 cases) or cardiovascular (1 case) manifestations or bleeding diathesis (4 cases). One in four patients had a precipitating factor that could have triggered the CC (
conclusionCeliac crisis is a rare but severe and potentially fatal clinical feature of CD. A high index of suspicion is needed to recognize this clinical entity and to deliver proper therapy consisting of supportive care and, subsequently, GFD.
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