Evidence map›Paper›PMID 30746281›Full record

ArticleTranslational neuroscience2018

Protective Effect of Extract of

Guoqing Zhao, Kai Li, Junyang Chen, Longyun Li

Open access · goldAbstract read
In one paragraph

Article in Translational neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Potential Protective Effects of Naringin on Oculo-Pulmonary Injury Induced by PMCurrent therapeutic research, clinical and experimental · 2020
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Guoqing ZhaoDepartment of anesthesiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China, 130033.
Kai LiDepartment of anesthesiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China, 130033.
Junyang ChenDepartment of anesthesiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China, 130033.
Longyun LiDepartment of anesthesiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China, 130033.
Jilin University · CNUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPresent investigation evaluates the neuroprotective effect of METHODOLOGY: Neuronal injury was induced by exposing the pups (P7) isoflurane (0.75%) in oxygen (30%) for the period of 6 hr and rats were treated with

resultsResult of the study reveals that treatment with BS significantly (p<0.01) reduces the neurological score compared to negative control group. Level of inflammatory cytokines in the serum and the expression of p-Akt, Bcl-xL and Bad protein were significantly attenuated in BS treated group. Moreover the cleaved caspase-3 and TUNEL positive cell was significantly (p<0.01) reduced in BS treated group compared to negative control group of rats.

conclusionPresent study concludes that ethanolic extract of

Indexed as

ApoptosisBletilla striataCytokinesIsofluraneNeuroprotective

Identifiers

PMID30746281
PMCPMC6368668
OpenAlexW2914032239

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.