Evidence map›Paper›PMID 30746135›Full record

ArticleClinical kidney journal2019

Mortality risk after herpes zoster infection in end-stage renal disease patients.

John H Ahn, Jennifer L Waller, Stephanie L Baer, Rhonda E Colombo, Mufaddal F Kheda, N Stanley Nahman, Jake E Turrentine

Open access · goldAbstract read
In one paragraph

Article in Clinical kidney journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

John H AhnDepartment of Medicine, Augusta University, Augusta, GA, USA.
Jennifer L WallerDepartment of Population Health Sciences, Augusta University, Augusta, GA, USA.
Stephanie L BaerDepartment of Medicine, Augusta University, Augusta, GA, USA.
Rhonda E ColomboDepartment of Medicine, Augusta University, Augusta, GA, USA.
Mufaddal F KhedaSouthwest Georgia Nephrology Clinic, PC, Albany, GA, USA.
N Stanley NahmanDepartment of Medicine, Augusta University, Augusta, GA, USA.
Jake E TurrentineDepartment of Medicine, Augusta University, Augusta, GA, USA.
Augusta University · USAugusta University Health · USCharlie Norwood VA Medical Center · USSouthwest Georgia Area Health Education Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEnd-stage renal disease (ESRD) patients have increased risk of developing herpes zoster (zoster) compared with the general population, but mortality risk is unknown. We assessed the risk of mortality in hospitalized ESRD patients with a diagnosis of zoster from the inpatient hospital files (as opposed to outpatient records) of the United States Renal Data System.

methodsThis study analyzed incident ESRD patients from 2006 to 2009. Based on an

resultsZoster was diagnosed in 2784 patients, 51% of whom died within 2 years, with a mean time to death of 8.1 months. Patients who died were more likely to be white and older, score higher on the Charlson Comorbidity Index (CCI) and have other clinical diagnoses besides CCI. Increased risk of death within 2 years was associated with older age (adjusted hazard ratio 1.03), malnutrition (1.31), bacteremia/septicemia (1.16) and increasing CCI (1.10). Zoster vaccine was administered to 27 patients, but the small number precluded analysis of its impact.

conclusionsMortality in ESRD patients with an inpatient zoster diagnosis is increased with older age and higher severity of clinical comorbidities. The role of zoster vaccination on mortality in this population remains to be defined.

Indexed as

dialysisherpes zostermortalityrisk factorsUnited States Renal Data System

Identifiers

PMID30746135
PMCPMC6366125
OpenAlexW2883580639

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.