Evidence map›Paper›PMID 30746054›Full record

ArticleJournal of oral & maxillofacial research

Denosumab Related Osteonecrosis of Jaw: a Case Report.

Marco Vinícius de Sales Lima, Jaqueline Rizzato, Daniella Varzea Gracindo Marques, Dárcio Kitakawa, Felipe da Silva Peralta, Alexandre Prado Scherma, Luis Felipe C S Carvalho

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Journal of oral & maxillofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Marco Vinícius de Sales LimaFaculdade De Odontologia, Da Universidade De Taubaté (Unitau), Taubaté - SPBrazil.
Jaqueline RizzatoFaculdade De Odontologia, Da Universidade De Taubaté (Unitau), Taubaté - SPBrazil.
Daniella Varzea Gracindo MarquesFaculdade De Odontologia, Da Universidade De Taubaté (Unitau), Taubaté - SPBrazil.
Dárcio KitakawaCentro Universitário Braz Cubas, Mogi das Cruzes-SPBrazil.
Felipe da Silva PeraltaFaculdade De Odontologia, Da Universidade De Taubaté (Unitau), Taubaté - SPBrazil.
Alexandre Prado SchermaFaculdade De Odontologia, Da Universidade De Taubaté (Unitau), Taubaté - SPBrazil.
Luis Felipe C S CarvalhoFaculdade De Odontologia, Da Universidade De Taubaté (Unitau), Taubaté - SPBrazil.
Universidade de Taubaté · BRUniversidade Braz Cubas · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis case report shows an affected postmenopausal patient with medicaments related osteonecrosis of the jaw injury associated with increased use of bisphosphonates and Prolia

methodsThe injury was located around a dental implant in region #24 and #25 and the patient complained of pain, bleeding, oedema, and halitosis for more than two months, that the dental implant had been installed five years before. According to the clinical findings, the patient presented the exposed and necrotic bone in the region of #24 and #25 and with the radiographs found, it was observed as extensive bone destruction adjacent to the dental implant.

resultsPatient was referred to the maxillofacial surgeon that performed the removal of bone sequestration and dental implant in the region affected. After that, the patient has been accompanied for a year.

conclusionsPatients taking medications for osteoporosis or cancer need to receive special attention from the dentist. Invasive procedures on the jaw bone of patients taking these medications may cause osteonecrosis of the jaw. When diagnosed, osteonecrosis of the jaw should be treated surgically in conjunction with antibiotic therapy and patients should be monitored.

Indexed as

bisphosphonatesdenosumabdrugsosteonecrosis

Identifiers

PMID30746054
PMCPMC6365882
OpenAlexW2907614653

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.