Evidence map›Paper›PMID 30745956›Full record

ArticleOpen access Macedonian journal of medical sciences2019

Improving Treatment Outcome of Pemphigus Vulgaris on Vietnamese Patients by Using Desmoglein Elisa Test.

Anh Tran Thi Van, Thuong Van Nguyen, Sau Nguyen Huu, Lan Pham Thi, Phuong Pham Thi Minh, NghiDinh Huu, Van Tran Cam, My Le Huyen, Minh Vu Nguyet, Khang Tran Hau and 6 more

Open access · diamondAbstract read
In one paragraph

Article in Open access Macedonian journal of medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Removable Prosthetic Treatment in Oral Pemphigus Vulgaris: Report of Three Cases.Journal of International Society of Preventive & Community Dentistry
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 3 countries.

Anh Tran Thi VanNational Hospital of Dermatology and Venereology, Hanoi, Vietnam.
Thuong Van NguyenNational Hospital of Dermatology and Venereology, Hanoi, Vietnam.
Sau Nguyen HuuNational Hospital of Dermatology and Venereology, Hanoi, Vietnam.
Lan Pham ThiNational Hospital of Dermatology and Venereology, Hanoi, Vietnam.
Phuong Pham Thi MinhNational Hospital of Dermatology and Venereology, Hanoi, Vietnam.
NghiDinh HuuNational Hospital of Dermatology and Venereology, Hanoi, Vietnam.
Van Tran CamNational Hospital of Dermatology and Venereology, Hanoi, Vietnam.
My Le HuyenNational Hospital of Dermatology and Venereology, Hanoi, Vietnam.
Minh Vu NguyetNational Hospital of Dermatology and Venereology, Hanoi, Vietnam.
Khang Tran HauNational Hospital of Dermatology and Venereology, Hanoi, Vietnam.
Marco GandolfiUnit of Dermatology, University of Parma, Parma, Italy.
Francesca SatolliUnit of Dermatology, University of Parma, Parma, Italy.
Claudio FelicianiUnit of Dermatology, University of Parma, Parma, Italy.
Michael TirantUniversity of Rome G. Marconi, Rome Italia.
Aleksandra VojvodicDepartment of Dermatology and Venereology, Military Medical Academy of Belgrade, Belgrade, Serbia.
Torello LottiPsoriasis Eczema Clinic, Melbourne, Australia.
National Hospital of Pediatrics · VNUniversity of Parma · ITMilitary Medical Academy · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPemphigus Vulgaris (PV) is a chronic disease, is characterized by the presence of flacid bullous in skin and mucosa. There are 2 main autoantibodies against desmoglein3 (Dsg3) and desmoglein1 (Dsg1).

aimThe aims of this study were to evaluate the before and after treatment outcome with corticosteroid, using Desmoglein ELISA test.

methodForty patients with Pemphigus include 36 PV and 4 PF (28 women, 12 women) were enrolled. The titers of Dsg in pemphigus patients by using ELISA test were done before and 1-month treatment.

resultsBoth anti-Dsg1 and anti-Dsg3 levels were significantly reduced after treatment (P < 0.05). The severity of skin lesions was correlated with anti-Dsg1 antibody level and the severity of oral lesions was significantly correlated with anti-Dsg 3 antibody levels (p < 0.05).

conclusionIt is recommended that we can predict and improve the outcome of treatment by using Desmoglein ELISA test.

Indexed as

DesmogleinELISAPemphigus

Identifiers

PMID30745956
PMCPMC6364727
OpenAlexW2913500667

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.