Evidence map›Paper›PMID 30745768›Full record

ArticleAnnals of pediatric cardiology

Outcome of pediatric cardiac surgery and predictors of major complication in a developing country.

Indah K Murni, Mulyadi M Djer, Piprim B Yanuarso, Sukman T Putra, Najib Advani, Jusuf Rachmat, Aries Perdana, Rubiana Sukardi

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Annals of pediatric cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07059689 (High Flow Nasal Cannula vs. Non-Invasive Ventilation in Post-Extubation Pediatric Cardiac Surgery Patients), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07059689 narecruitingnot on this map

High Flow Nasal Cannula vs. Non-Invasive Ventilation in Post-Extubation Pediatric Cardiac Surgery Patients: A Randomized Controlled Trial

TypeinterventionalSponsorIndonesia UniversityRan2025 to 2025Enrolled114ConditionsHeart Defects, Congenital, Intensive Care Units, Pediatric, Respiration, Artificial, ExtubationArmsHigh Flow Nasal Cannula (HFNC), Non-Invasive Ventilation (NIV)
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

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  10. Evaluation of perioperative risk factors in pediatric patients with left ventricle outflow tract obstruction.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Indah K MurniDepartment of Pediatrics, Faculty of Medicine, Dr. Sardjito Hospital, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Mulyadi M DjerDepartment of Child Health, Dr. Cipto Mangunkusumo Hospital, University of Indonesia, Jakarta, Indonesia.
Piprim B YanuarsoDepartment of Child Health, Dr. Cipto Mangunkusumo Hospital, University of Indonesia, Jakarta, Indonesia.
Sukman T PutraDepartment of Child Health, Dr. Cipto Mangunkusumo Hospital, University of Indonesia, Jakarta, Indonesia.
Najib AdvaniDepartment of Child Health, Dr. Cipto Mangunkusumo Hospital, University of Indonesia, Jakarta, Indonesia.
Jusuf RachmatDepartment of Cardio-Thoracic Surgery, Dr. Cipto Mangunkusumo Hospital, University of Indonesia, Jakarta, Indonesia.
Aries PerdanaDepartment of Anesthesiology, Dr. Cipto Mangunkusumo Hospital, University of Indonesia, Jakarta, Indonesia.
Rubiana SukardiIntegrated Cardiac Centre, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo · IDUniversitas Gadjah Mada · IDUniversity of Indonesia · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEvaluating outcome and identifying predictors of major complications among children undergoing cardiac surgery are essential to improve care. We evaluated short-term outcomes of postcardiac surgery and predictors of major complications in a national referral hospital in Indonesia.

methodsA prospective cohort study was conducted from April 2014 to March 2015 on all children undergoing cardiac surgery. Participants were followed up from the time of surgery until hospital discharge and 30-day mortality. We performed univariate and multivariate logistic regression using STATA 12-1 to identify predictors of postsurgical major complications.

resultsA total of 257 patients (median age: 36 months) were recruited; 217 (84.1%) had complications, including low cardiac output syndrome (19.8%), arrhythmia (18.6%), sepsis (17.4%), and pleural effusion (14.8%). Forty-nine (19%) patients had major complications, including cardiac arrest (5%), need for emergency chest opening (3.9%), and multiple organ failure (7.4%). 12.8% died during hospital stay, and 30-day mortality was 13.6%. Predictors of major complications were cyanotic congenital heart disease (odds ratio [OR]: 4.6, 95% confidence interval [CI]: 1.5-14.2), longer duration of cardiopulmonary bypass (CPB, OR: 4.4, 95% CI: 1.5-13.4), high inotropes (OR: 13.1, 95% CI: 3.2-54.2), and increase in lactate >0.75 mmol/L/h or more in the first 24 h (OR: 37.1, 95% CI: 10.1-136.3).

conclusionOne-fifth of children undergoing cardiac surgery experienced major complications with around 13% mortality. Cyanotic congenital heart disease, longer duration of CPB, high inotropes on leaving operating theater, and increase in blood lactate are associated with major complications in children after cardiac surgery.

Indexed as

Cardiac surgerychildrencomplicationmortalityoutcomepredictor

Identifiers

PMID30745768
PMCPMC6343386
OpenAlexW2911110553

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.