ArticleIndian journal of anaesthesia2019
Cancer relapse in surgical patients who received perioperative transfusion of blood and blood products: A case-control study.
Article in Indian journal of anaesthesia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
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Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.
- Enhanced Functional and Surgical Outcomes With 3D Printing in Orthopedic Oncology: A Comparative Meta-Analysis Against Conventional Techniques.Journal of surgical oncology · 2025Pooled it
- The safety, tolerability and clinical impact of pre-operative very low-calorie diet prior to non-bariatric abdominal surgery: a systematic review.Langenbeck's archives of surgery · 2024Pooled it
- Lower need for allogeneic blood transfusion after robotic low anterior resection compared with open low anterior resection: a propensity score-matched analysis.Journal of robotic surgery · 2023Article
- Evaluation of efficacy and safety of a single dose Tranexamic acid in reducing blood loss during colorectal cancer surgery. A randomised, placebo controlled, double-blinded study.Indian journal of anaesthesia · 2023Article
- Recent advances in perioperative blood management.Indian journal of anaesthesia · 2023Article
- Appropriateness of red cell transfusion practices in an intensive care unit: A prospective observational study.Indian journal of anaesthesia · 2022Article
- Preoperative incremental shuttle walk test for morbidity and mortality prediction in elective major colorectal surgery.Indian journal of anaesthesia · 2022Article
- A tripartite challenge of orphaned manuscripts, heedless writing and reluctant reviewing...... revamping the editing process!Indian journal of anaesthesia · 2021Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsImmunomodulatory consequences of allogeneic blood transfusion may outweigh the advantages of improved oxygen delivery and tissue perfusion, especially in patients with cancer. In colorectal cancer, there is evidence of cancer relapse in patients who received transfusion. This retrospective analysis was undertaken to evaluate the relationship between perioperative blood transfusion and cancer recurrence in patients undergoing oncosurgery.
methodsIn this case-control study, we retrospectively analysed the case sheets of 194 patients who had perioperative transfusion and underwent cancer surgery from March to December 2013(Study group, Cases). They were compared with controls matched for cancer site and TNM staging who did not receive perioperative transfusions (Control Group, Controls). We intended to find out if the Study group had any increased risk of cancer relapse compared with the controls. Records from the institute cancer registry were analysed in 2018 to give a follow-up period of 5 years. Continuous variables were analysed using Student's T test and Mann Whitney U test for normally distributed and skewed data respectively. For Categorical data Fisher's exact test and Chi square test were applied. The risk for recurrence was estimated using odds ratio.
resultsThe recurrence rate in cases and controls was 53.09% and 19.59% respectively and the odds ratio, 4.647 (CI: 2.954, 7.309). In Cases, significant relapse was noted for carcinomas of ovary, colorectal, bladder, larynx, head of pancreas and liver.
conclusionIn surgical oncology patients, ABT is associated with greater rate of recurrence.
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