Evidence map›Paper›PMID 30745455›Full record

ArticleBioscience reports2019

Autophagy induced by SAHA affects mutant P53 degradation and cancer cell survival.

Giorgia Foggetti, Laura Ottaggio, Debora Russo, Carlotta Mazzitelli, Paola Monti, Paolo Degan, Mariangela Miele, Gilberto Fronza, Paola Menichini

Open access · goldAbstract read
In one paragraph

Article in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
  2. Targeting the p53/xCT/GSH Axis with PRIMA-1International journal of molecular sciences · 2025
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Gain of Function (GOF) Mutant p53 in Cancer-Current Therapeutic Approaches.International journal of molecular sciences · 2022
    Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Mutant p53Frontiers in genetics · 2022
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Giorgia FoggettiMutagenesis and Cancer Prevention Unit, IRCCS Ospedale Policlinico San Martino, Genoa 16132, Italy.
Laura OttaggioMutagenesis and Cancer Prevention Unit, IRCCS Ospedale Policlinico San Martino, Genoa 16132, Italy.
Debora RussoMutagenesis and Cancer Prevention Unit, IRCCS Ospedale Policlinico San Martino, Genoa 16132, Italy.
Carlotta MazzitelliMutagenesis and Cancer Prevention Unit, IRCCS Ospedale Policlinico San Martino, Genoa 16132, Italy.
Paola MontiMutagenesis and Cancer Prevention Unit, IRCCS Ospedale Policlinico San Martino, Genoa 16132, Italy.
Paolo DeganMutagenesis and Cancer Prevention Unit, IRCCS Ospedale Policlinico San Martino, Genoa 16132, Italy.
Mariangela MieleMutagenesis and Cancer Prevention Unit, IRCCS Ospedale Policlinico San Martino, Genoa 16132, Italy.
Gilberto FronzaMutagenesis and Cancer Prevention Unit, IRCCS Ospedale Policlinico San Martino, Genoa 16132, Italy.
Paola MenichiniMutagenesis and Cancer Prevention Unit, IRCCS Ospedale Policlinico San Martino, Genoa 16132, Italy paola.menichini@hsanmartino.it.ORCID 0000-0003-0057-6184
Ospedale Policlinico San Martino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Missense mutations in the

Indexed as

Antineoplastic AgentsApoptosisAutophagyBreast NeoplasmsCell Line, TumorCell SurvivalFemaleHistone Deacetylase InhibitorsHumansMutationProteolysisTumor Suppressor Protein p53VorinostatAntineoplastic AgentsHistone Deacetylase InhibitorsTP53 protein, humanTumor Suppressor Protein p53Vorinostatapoptosisautophagymutant p53SAHA

Identifiers

PMID30745455
PMCPMC6379511
OpenAlexW2914597730

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.