Evidence map›Paper›PMID 30745370›Full record

ArticleJournal of bacteriology2019

tRNA Modification Profiles and Codon-Decoding Strategies in Methanocaldococcus jannaschii.

Ningxi Yu, Manasses Jora, Beulah Solivio, Priti Thakur, Carlos G Acevedo-Rocha, Lennart Randau, Valérie de Crécy-Lagard, Balasubrahmanyam Addepalli, Patrick A Limbach

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Archaeal RNA processing and regulation: expanding the functional landscape.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  6. Review
  7. Article
  8. The Landscape of tRNA Modifications in Archaea.bioRxiv : the preprint server for biology · 2025
    Article
  9. Article
  10. Stress-induced modification ofProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Direct sequencing of totalRNA (New York, N.Y.) · 2023
    Article
  16. Identification of URNA (New York, N.Y.) · 2023
    Article
  17. Article
  18. Review
  19. Article
  20. Highlighting the Unique Roles of RadicalJournal of bacteriology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Ningxi YuRieveschl Laboratories for Mass Spectrometry, Department of Chemistry, University of Cincinnati, Cincinnati, Ohio, USA.
Manasses JoraRieveschl Laboratories for Mass Spectrometry, Department of Chemistry, University of Cincinnati, Cincinnati, Ohio, USA.
Beulah SolivioRieveschl Laboratories for Mass Spectrometry, Department of Chemistry, University of Cincinnati, Cincinnati, Ohio, USA.
Priti ThakurRieveschl Laboratories for Mass Spectrometry, Department of Chemistry, University of Cincinnati, Cincinnati, Ohio, USA.
Carlos G Acevedo-RochaMax Planck Institute for Terrestrial Microbiology, Marburg, Germany.
Lennart RandauMax Planck Institute for Terrestrial Microbiology, Marburg, Germany.
Valérie de Crécy-LagardDepartment of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, Florida, USA.
Balasubrahmanyam AddepalliRieveschl Laboratories for Mass Spectrometry, Department of Chemistry, University of Cincinnati, Cincinnati, Ohio, USA.
Patrick A LimbachRieveschl Laboratories for Mass Spectrometry, Department of Chemistry, University of Cincinnati, Cincinnati, Ohio, USA Pat.Limbach@uc.edu.ORCID 0000-0003-1526-4546
University of Cincinnati · USMax Planck Institute for Terrestrial Microbiology · DEUniversity of Florida · US

Funding

Synthesis and function of Queuosine in BacteriaR01GM070641 · NIGMS · UNIVERSITY OF FLORIDA · PI DE CRECY-LAGARD, VALERIE A · 2006 to 2023
$5.3M
NIGMS NIH HHS R01 GM070641
6 · The paper itself

Abstract

tRNAs play a critical role in mRNA decoding, and posttranscriptional modifications within tRNAs drive decoding efficiency and accuracy. The types and positions of tRNA modifications in model bacteria have been extensively studied, and tRNA modifications in a few eukaryotic organisms have also been characterized and localized to particular tRNA sequences. However, far less is known regarding tRNA modifications in archaea. While the identities of modifications have been determined for multiple archaeal organisms,

Indexed as

AnticodonProtein BiosynthesisRNA Processing, Post-TranscriptionalMethanocaldococcusRNA, TransferAnticodonRNA, Transfer5-cyanomethyl-2-thiouridineanticodon looparchaeaLC-MS/MSmodified nucleosidesposttranscriptional modificationtRNA

Identifiers

PMID30745370
PMCPMC6456858
OpenAlexW2911312815

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.