ArticleThe Journal of experimental medicine2019
Chronic virus infection compromises memory bystander T cell function in an IL-6/STAT1-dependent manner.
Article in The Journal of experimental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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Who cites it
18 citing papers in PubMed.
- T-Cell Profiles in HBV Functional Cure and People Living With HIV: Known Knowns, Known Unknowns, and Unknown Unknowns.Current HIV/AIDS reports · 2026Review
- Memory CD8 T cells are vulnerable to chronic IFN-γ signals but not to CD4 T cell deficiency in MHCII-deficient mice.Nature communications · 2024Article
- Simultaneous analysis of pMHC binding and reactivity unveils virus-specific CD8 T cell immunity to a concise epitope set.Science advances · 2024Article
- Chronic viral infection impairs immune memory to a different pathogen.PLoS pathogens · 2024Article
- Neuro-PASC is characterized by enhanced CD4+ and diminished CD8+ T cell responses to SARS-CoV-2 Nucleocapsid protein.Frontiers in immunology · 2023Article
- Exercise-induced engagement of the IL-15/IL-15Rα axis promotes anti-tumor immunity in pancreatic cancer.Cancer cell · 2022Article
- Article
- Effect of cellular aging on memory T-cell homeostasis.Frontiers in immunology · 2022Article
- Clonally Expanded Virus-Specific CD8 T Cells Acquire Diverse Transcriptional Phenotypes During Acute, Chronic, and Latent Infections.Frontiers in immunology · 2022Article
- The mechanism of colon tissue damage mediated by HIF-1α/NF-κB/STAT1 in high-altitude environment.Frontiers in physiology · 2022Article
- Using 2D and 3D pluripotent stem cell models to study neurotropic viruses.Frontiers in virology (Lausanne, Switzerland) · 2022Article
- Review
- Systemic immunity in cancer.Nature reviews. Cancer · 2021Review
- The Ugly Duckling Turned to Swan: A Change in Perception of Bystander-Activated Memory CD8 T Cells.Journal of immunology (Baltimore, Md. : 1950) · 2021Review
- Chronic viral infections impinge on naive bystander CD8 T cells.Immunity, inflammation and disease · 2020Article
- Systemic dysfunction and plasticity of the immune macroenvironment in cancer models.Nature medicine · 2020Article
- T Cell-Intrinsic IL-6R Signaling Is Required for Optimal ICOS Expression and Viral Control during Chronic Infection.Journal of immunology (Baltimore, Md. : 1950) · 2019Article
- Stand by me(mory): Chronic infection diminishes memory pool via IL-6/STAT1.The Journal of experimental medicine · 2019Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic viral infections are widespread among humans, with ∼8-12 chronic viral infections per individual, and there is epidemiological proof that these impair heterologous immunity. We studied the impact of chronic LCMV infection on the phenotype and function of memory bystander CD8
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.