Evidence map›Paper›PMID 30744968›Full record

ArticleCurrent biology : CB2019

Kisspeptin Neurons in the Arcuate Nucleus of the Hypothalamus Orchestrate Circadian Rhythms and Metabolism.

Stephanie L Padilla, Jazmine G Perez, Miriam Ben-Hamo, Christopher W Johnson, Raymond E A Sanchez, Ivana L Bussi, Richard D Palmiter, Horacio O de la Iglesia

Open access · bronzeAbstract read
In one paragraph

Article in Current biology : CB, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
6.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 111 citations in OpenAlex.

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  8. Sex-specific thermoregulatory effects of estrogen signaling inbioRxiv : the preprint server for biology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Stephanie L PadillaHoward Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA. Electronic address: slpadilla@umass.edu.
Jazmine G PerezDepartment of Biology, University of Washington, Seattle, WA 98195, USA.
Miriam Ben-HamoDepartment of Biology, University of Washington, Seattle, WA 98195, USA.
Christopher W JohnsonGraduate Program in Neuroscience, University of Washington, Seattle, WA 98195, USA.
Raymond E A SanchezDepartment of Biology, University of Washington, Seattle, WA 98195, USA; Graduate Program in Neuroscience, University of Washington, Seattle, WA 98195, USA.
Ivana L BussiDepartment of Biology, University of Washington, Seattle, WA 98195, USA.
Richard D PalmiterHoward Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA.
Horacio O de la IglesiaDepartment of Biology, University of Washington, Seattle, WA 98195, USA. Electronic address: horaciod@uw.edu.
University of Washington · USHoward Hughes Medical Institute · US

Funding

Effect of Killing or Removing GABA from NPY/AgRP NeuronsR01DA024908 · NIDA · UNIVERSITY OF WASHINGTON · PI PALMITER, RICHARD D. · 2007 to 2021
$3.5M
Role of GABA on circadian and homeostatic regulation of sleepR01NS094211 · NINDS · UNIVERSITY OF WASHINGTON · PI DE LA IGLESIA, HORACIO O · 2015 to 2018
$1.4M
NIDA NIH HHS R01 DA024908NINDS NIH HHS R01 NS094211
6 · The paper itself

Abstract

Successful reproduction in female mammals is precisely timed and must be able to withstand the metabolic demand of pregnancy and lactation. We show that kisspeptin-expressing neurons in the arcuate hypothalamus (Kiss1

Indexed as

AnimalsArcuate Nucleus of HypothalamusBody TemperatureCircadian RhythmFeeding BehaviorFemaleKisspeptinsLocomotionMiceNeuronsSleepKiss1 protein, mouseKisspeptinsbody temperaturebody weightcircadian rhythmestrogenkisspeptinmenopauseneural circuitsneurophysiologyshift worksleep

Identifiers

PMID30744968
PMCPMC7147454
OpenAlexW2914272305

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.