Evidence map›Paper›PMID 30744701›Full record

Observational studyBMC cardiovascular disorders2019

Interatrial block in prediction of all-cause mortality after first-ever ischemic stroke.

M A Baturova, A Lindgren, Y V Shubik, J Carlson, P G Platonov

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC cardiovascular disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  7. [Bayés Syndrome, Stroke and Dementia].Archivos peruanos de cardiologia y cirugia cardiovascular
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

M A BaturovaDepartment of Cardiology, Clinical Sciences, Lund University, SE-221 85, Lund, Sweden. Maria.Baturova@med.lu.se.ORCID 0000-0003-3811-6810
A LindgrenDepartment of Cardiology, Clinical Sciences, Lund University, SE-221 85, Lund, Sweden.
Y V ShubikCardiology research, clinical and educational center, St. Petersburg State University, Universitetskaya Embankment, 7/9, St. Petersburg, Russia.
J CarlsonDepartment of Cardiology, Clinical Sciences, Lund University, SE-221 85, Lund, Sweden.
P G PlatonovDepartment of Cardiology, Clinical Sciences, Lund University, SE-221 85, Lund, Sweden.
Lund University · SESt Petersburg University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInteratrial block (IAB) is an ECG indicator of atrial fibrosis related to atrial remodeling and thrombus formation thus leading to embolic stroke and increasing mortality. We aimed to assess weather IAB predicted all-cause mortality during 10 years after ischemic stroke.

methodsThe study sample comprised 235 patients (median age 74 (interquartile range 25-75% 65-81) years, 95 female) included in the Lund Stroke Register in 2001-2002, who had sinus rhythm ECGs at stroke admission. IAB was defined as a P-wave duration ≥120 ms without = partial IAB (n = 56) or with = advanced IAB (n = 41) biphasic morphology (±) in the inferior ECG leads. All-cause mortality was assessed via linkage with the Swedish Causes of Death Register.

resultsDuring follow-up 126 patients died (54%). Advanced IAB, but not partial, was associated with all-cause mortality in univariate Cox regression analysis (hazard ratio (HR) 1.98, 95% CI 1.27-3.09, p = 0.003). After adjustment for age, gender, severity of stroke measured by NIHSS scale and smoking status in patients without additional comorbidities advanced IAB independently predicted all-cause mortality (HR 7.89, 95% CI 2.01-30.98, p = 0.003), while in patients with comorbidities it did not (HR 1.01 95% CI 0.59-1.72, p = 0.966).

conclusionAdvanced IAB predicted all-cause mortality after ischemic stroke, but mostly in patients without additional cardiovascular comorbidities.

Indexed as

AgedAged, 80 and overAtrial RemodelingBrain IschemiaCause of DeathFemaleFibrosisHumansInteratrial BlockMalePredictive Value of TestsPrognosisRegistriesRetrospective StudiesRisk AssessmentRisk FactorsAll-cause mortalityAtrial fibrosisECGInteratrial blockIschemic stroke

Identifiers

PMID30744701
PMCPMC6371419
OpenAlexW2917456865

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.