Evidence map›Paper›PMID 30744665›Full record

ArticleParasites & vectors2019

A previously unreported potential malaria vector in a dry ecology of Kenya.

Edwin O Ogola, Edith Chepkorir, Rosemary Sang, David P Tchouassi

Open access · goldAbstract read
In one paragraph

Article in Parasites & vectors, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

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  13. Characterizing the Spatial Determinants and Prevention of Malaria in Kenya.International journal of environmental research and public health · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Edwin O OgolaInternational Centre of Insect Physiology and Ecology (icipe), P.O. Box 30772-00100, Nairobi, Kenya.
Edith ChepkorirInternational Centre of Insect Physiology and Ecology (icipe), P.O. Box 30772-00100, Nairobi, Kenya.
Rosemary SangInternational Centre of Insect Physiology and Ecology (icipe), P.O. Box 30772-00100, Nairobi, Kenya.
David P TchouassiInternational Centre of Insect Physiology and Ecology (icipe), P.O. Box 30772-00100, Nairobi, Kenya. dtchouassi@icipe.org.ORCID http://orcid.org/0000-0001-9910-4704
International Centre of Insect Physiology and Ecology · KE

Funding

The study was funded by a grant from the Foundation for the National Institutes of Health through the Vector-Based Transmission of Control: Discovery Research (VCTR) program of the Grand Challenges in Global Health initiative. Additionally, we gratefully acknowledge the financial support for this research by the following organizations and agencies: UK's Department for International Development (DFID); Swedish International Development Cooperation Agency (Sida); the Swiss Agency for Development and Cooperation (SDC); and the Kenyan Government. The views expressed herein do not necessarily reflect the official opinion of the donors. NA
6 · The paper itself

Abstract

backgroundIn Kenya, malaria remains a major public health menace equally affecting the semi-arid to arid ecologies. However, entomologic knowledge of malaria vectors in such areas remains poor.

methodsMorphologically-identified wild-caught Anopheles funestus (s.l.) specimens trapped outdoors from the semi-arid to arid area of Kacheliba, West Pokot County, Kenya, were analysed by PCR and sequencing for species identification, malaria parasite infection and host blood-meal sources.

resultsThree hundred and thirty specimens were analysed to identify sibling species of the An. funestus group, none of which amplified using the available primers; two were infected with Plasmodium falciparum and Plasmodium ovale, separately, while 84% (n = 25) of the blood-fed specimens had fed on humans. Mitochondrial cytochrome c oxidase subunit 1 (cox1) and nuclear ribosomal internal transcribed spacer 2 (ITS2) sequences of 55 specimens (Plasmodium-positive, blood-fed and Plasmodium-negative) did not match reference sequences, possibly suggesting a previously unreported species, resolving as two clades.

conclusionsOur findings indicate the existence of yet-to-be identified and described anopheline species with a potential as malaria vectors in Kenya.

Indexed as

AnimalsAnophelesDNA, ProtozoanDNA, Ribosomal SpacerEcologyElectron Transport Complex IVEnvironmental MonitoringFemaleHumansKenyaMalariaMitochondriaMosquito VectorsPlasmodium falciparumPolymerase Chain ReactionSequence Analysis, DNADNA, ProtozoanDNA, Ribosomal SpacerElectron Transport Complex IVAnopheles funestus groupDry ecologyEntomological surveillanceKenyaMalaria transmissionMolecular approaches

Identifiers

PMID30744665
PMCPMC6369554
OpenAlexW2921094202

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.