Observational studyBMC pulmonary medicine2019
Prognostic values of the Berlin definition criteria, blood lactate level, and fibroproliferative changes on high-resolution computed tomography in ARDS patients.
Observational study in BMC pulmonary medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.
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Who cites it
28 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Predictive Value of the PaOInternal medicine (Tokyo, Japan) · 2025Pooled it
- Predictive value of computed tomography for short-term mortality in patients with acute respiratory distress syndrome: a systematic review.Scientific reports · 2022Pooled it
- Effect of different levels of PEEP on mortality in ICU patients without acute respiratory distress syndrome: systematic review and meta-analysis with trial sequential analysis.Journal of critical care · 2021Pooled it
- Article
- Prognostic value of the PaOBMJ open · 2025Observational
- Prognostic significance of lactate/albumin ratio in respiratory failure and sepsis.Annals of medicine · 2025Article
- A prediction model for 30-day mortality in patients with ARDS admitted to the intensive care unit.European journal of medical research · 2025Article
- Impact of low dose inhaled nitric oxide treatment in spontaneously breathing and intubated COVID-19 patients: a retrospective propensity-matched study.Critical care (London, England) · 2024Article
- Serum β2-microglobulin as an independent risk factor for mortality in patients with acute respiratory distress syndrome caused by bacterial infection.Scientific reports · 2024Article
- Chest CT findings in severe acute respiratory distress syndrome requiring V-V ECMO: J-CARVE registry.Journal of intensive care · 2024Article
- Stability and structure-activity relationship of the SPA4 peptide under ambient and stressed conditions of lung injury.RSC advances · 2023Article
- Collaborative strategies for deploying artificial intelligence to complement physician diagnoses of acute respiratory distress syndrome.NPJ digital medicine · 2023Article
- Development and validation of a rabbit model ofFrontiers in cellular and infection microbiology · 2023Article
- Respiratory Subsets in Patients with Moderate to Severe Acute Respiratory Distress Syndrome for Early Prediction of Death.Journal of clinical medicine · 2022Review
- ARDS Clinical Practice Guideline 2021.Journal of intensive care · 2022Article
- Estimating the incidence of spontaneous breathing effort of mechanically ventilated patients using a non-linear auto regressive (NARX) model.Computer methods and programs in biomedicine · 2022Article
- Effects of High-Resolution CT Changes on Prognosis Predictability in Acute Respiratory Distress Syndrome with Diffuse Alveolar Damage.Journal of clinical medicine · 2022Article
- Relationship between Mechanical Ventilation and Histological Fibrosis in Patients with Acute Respiratory Distress Syndrome Undergoing Open Lung Biopsy.Journal of personalized medicine · 2022Article
- Short-term protective effect of octreotide on the lungs of rats with experimentally induced sepsis.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
- Effect of Dihydropyridine Calcium Channel Blocker on Mortality of Hypertension Patients With Moderate-Severe Pulmonary Acute Respiratory Distress Syndrome: A Multicenter Retrospective Observational Cohort Study.Critical care explorations · 2021Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn the Berlin definition, acute respiratory distress syndrome (ARDS) is stratified into three stages according to oxygenation severity at the onset. The relevance between ARDS severity and prognosis varies among published reports and has not been verified, especially in Asian patients.
methodsIn this study, we examined the associations between the Berlin definition criteria and prognosis and clinical parameters, including high-resolution computed tomography (HRCT) scores of fibroproliferative changes of the lungs. One hundred fifty-three patients (45 females; mean age, 67 y/o), who met the Berlin definition and received treatment in our intensive care unit between January 2012 and December 2015, were enrolled.
resultsThe severity of ARDS was mild in 42 patients, moderate in 71, and severe in 40. The underlying diseases included pneumonia in 56 patients and aspiration in 43. Forty-two (27.5%) patients were deceased within 30 days, and the 30-day mortality was 10% in mild ARDS, 23% in moderate, and 55% in severe, which were significantly different (P < 0.05). In the non-survivors, APACHE II, SOFA, and SAPS II scores were higher than in the survivors (P < 0.001). Multivariate analyses revealed that elevated blood lactate level (≥ 2.0 mmol/L) and increased HRCT scores were significantly associated with weaning failure and 30-day mortality of the patients with ARDS.
conclusionsThese results suggested that the severity criteria in the Berlin definition might be associated with the prognosis of the patients. Blood lactate levels and HRCT score might be predictive of the outcome of patients with ARDS.
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