ArticleBMC medical imaging2019
CoreSlicer: a web toolkit for analytic morphomics.
Article in BMC medical imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05367284 (Use of Perioperative Testosterone Replacement Therapy), which is not on this map. Cited by 44 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Use of Perioperative Testosterone Replacement Therapy (TRT) in Sarcopenic Male Colorectal Cancer Patients - A Single Arm Open Label Feasibility Study
Who cites it
44 citing papers in PubMed.
- Body composition measurements and clinical outcomes in patients with resectable pancreatic adenocarcinoma - analysis from SWOG S1505.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2024Trial
- Decision-making for older adults with advanced heart disease: a framework for balancing benefit versus futility.European heart journal · 2026Review
- Muscle mass and quality by computed tomography predicts mortality and emergency department revisits in older adults with acute pulmonary embolism.Journal of thrombosis and thrombolysis · 2026Article
- Computed tomography derived morphomics in the prediction of long-term outcomes in acute pancreatitis.World journal of radiology · 2026Article
- Integration of sarcopenia screening into radiotherapy planning: Validation of a time-efficient SMI measurement method using MIM software in prostate cancer.Journal of applied clinical medical physics · 2026Article
- A Retrospective Study of Outcome Predictive Models for Anterior Circulation Stroke Post-Endovascular Thrombectomy: Are CT-Derived Morphomics Useful?Cerebrovascular diseases extra · 2026Article
- Bioelectrical impedance compared to computed tomography for muscle mass evaluation in critically ill elderly patients.Critical care science · 2026Article
- Sarcopenia in Older Patients with Newly Diagnosed Multiple Myeloma.Gerontology · 2026Article
- Multimodal Prehabilitation in Indian Women with Advanced Ovarian Cancer: Enhancing Nutritional, Psychological, and Surgical Recovery.Asian Pacific journal of cancer prevention : APJCP · 2025Article
- Rifaximin-α use is associated with improved muscle mass in patients with cirrhosis.World journal of hepatology · 2025Article
- Stand-alone MRI tool for semiautomatic volumetry of abdominal adipose compartments in patients with obesity.Scientific reports · 2025Article
- Subcutaneous and Visceral Adipose Tissue Reference Values From the Framingham Heart Study Thoracic and Abdominal CT.Investigative radiology · 2025Observational
- Ultrasound Segmentation Using Semi-Supervised Learning: Application in Point-of-Care Sarcopenia Assessment.IEEE open journal of engineering in medicine and biology · 2025Article
- Body Composition and Progression of Biopsy-Proven Non-Alcoholic Fatty Liver Disease in Patients With Obesity.Journal of cachexia, sarcopenia and muscle · 2024Article
- A Cross-Sectional Validation of Horos and CoreSlicer Software Programs for Body Composition Analysis in Abdominal Computed Tomography Scans in Colorectal Cancer Patients.Diagnostics (Basel, Switzerland) · 2024Article
- Muscle matters: Skeletal muscle index and body mass index impact on complications and survival in renal cancer.BJUI compass · 2024Article
- Sarcopenia and aortic valve disease.Heart (British Cardiac Society) · 2024Review
- Quantification of Visceral Fat at the L5 Vertebral Body Level in Patients with Crohn's Disease Using T2-Weighted MRI.Bioengineering (Basel, Switzerland) · 2024Article
- The Relationship of Pathological Response and Visceral Muscle and Fat Volume in Women With Breast Cancer Who Received Neoadjuvant Chemotherapy.European journal of breast health · 2024Article
- Poor Sit-to-Stand Performance in Adolescent and Young Adult Patients with Sarcoma.Journal of adolescent and young adult oncology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
backgroundAnalytic morphomics, or more simply, "morphomics," refers to the measurement of specific biomarkers of body composition from medical imaging, most commonly computed tomography (CT) images. An emerging body of literature supports the use of morphomic markers measured on single-slice CT images for risk prediction in a range of clinical populations. However, uptake by healthcare providers been limited due to the lack of clinician-friendly software to facilitate measurements. The objectives of this study were to describe the interface and functionality of CoreSlicer- a free and open-source web-based interface aiming to facilitate measurement of analytic morphomics by clinicians - and to validate muscle and fat measurements performed in CoreSlicer against reference software.
resultsMeasurements of muscle and fat obtained in CoreSlicer show high agreement with established reference software. CoreSlicer features a full set of DICOM viewing tools and extensible plugin interface to facilitate rapid prototyping and validation of new morphomic markers by researchers. We present published studies illustrating the use of CoreSlicer by clinicians with no prior knowledge of medical image segmentation techniques and no formal training in radiology, where CoreSlicer was successfully used to predict operative risk in three distinct populations of cardiovascular patients.
conclusionsCoreSlicer enables extraction of morphomic markers from CT images by non-technically skilled clinicians. Measurements were reproducible and accurate in relation to reference software.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.