Observational studyNutrients2019
Insufficient Nutrition and Mortality Risk in Septic Patients Admitted to ICU with a Focus on Immune Dysfunction.
Observational study in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04396522 (Application of Serial Body Composition Change for Risk Prediction in Treating Patients With Severe Pneumonia), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Application of Serial Body Composition Change for Risk Prediction in Treating Patients With Severe Pneumonia
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Impact of nutritional support on mortality among critically ill patients with different nutritional risks: a systematic review with meta-analysis.Frontiers in nutrition · 2025Pooled it
- Using Body Composition Analysis for Improved Nutritional Intervention in Septic Patients: A Prospective Interventional Study.Nutrients · 2023Trial
- Comparison of the NUTRIC-PNI score and NUTRIC score to assess nutritional risk and predict 28-day mortality in critically ill patients: a prospective cohort study in Vietnam.Acute and critical care · 2026Article
- Association between prognostic nutritional index and mortality in patients with sepsis-associated delirium: a retrospective cohort study using the MIMIC-IV database.BMC nutrition · 2026Article
- Analysis of the predictive value of 3-day cumulative energy deficit for 28-day mortality in patients with sepsis and nutritional risk: a retrospective study.Frontiers in nutrition · 2026Article
- Article
- Sepsis in multimorbidity: a domain-based framework for systemic vulnerability and precision care.Frontiers in medicine · 2026Review
- Research Progress of Sepsis and Nutrition: A Bibliometric and Visualized Analysis.Journal of inflammation research · 2026Article
- Can Nutritional Screening Tools Predict the Prognosis of Critically Ill Patients with Sepsis?Medicina (Kaunas, Lithuania) · 2025Observational
- Leptin and Iinterlukin-6 relationship and influence of mortality in sepsis.BMC infectious diseases · 2025Article
- Prognostic value of the Geriatric Nutritional Risk Index in mortality prediction among critically ill acute myocardial infarction patients.BMC cardiovascular disorders · 2025Article
- Dietary patterns and micronutrients in respiratory infections including COVID-19: a narrative review.BMC public health · 2024Review
- Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies.Journal of personalized medicine · 2024Review
- Prior Evaluation of Nutritional Status and Mortality in Patients with Sepsis in South Korea.Nutrients · 2023Article
- The NUTRIC Score as a Tool to Predict Mortality and Increased Resource Utilization in Intensive Care Patients with Sepsis.Nutrients · 2023Article
- Association of Hypernatremia with Immune Profiles and Clinical Outcomes in Adult Intensive Care Unit Patients with Sepsis.Biomedicines · 2022Article
- Dynamic monitoring of kidney injury status over 3 days in the intensive care unit as a sepsis phenotype associated with hospital mortality and hyperinflammation.Biomedical journal · 2022Article
- Review
- The Survival of Septic Patients with Compensated Liver Cirrhosis Is Not Inferior to That of Septic Patients without Liver Cirrhosis: A Propensity Score Matching Analysis.Journal of clinical medicine · 2022Article
- Impact of Body Mass Index on the Survival of Patients with Sepsis with Different Modified NUTRIC Scores.Nutrients · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Immune dysfunction is seen both in sepsis patients and in those with malnutrition. This study aimed to determine whether insufficient nutrition and immune dysfunction have a synergistic effect on mortality in critically ill septic patients. We conducted a prospective observational study from adult sepsis patients admitted to intensive care units (ICUs) between August 2013 and June 2016. Baseline characteristics including age, gender, body mass index, NUTRIC, Acute Physiology and Chronic Health Evaluation (APACHE) II and Sequential Organ Failure Assessment (SOFA) scores were recorded. Immune dysfunction, defined by human leukocyte antigen DR (HLA-DR) expression, was tested at days 1, 3, and 7 of ICU admission. The study included 151 patients with sepsis who were admitted to the ICU. The 28-day survivors had higher day 7 caloric intakes (89% vs 73%,
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.