Evidence map›Paper›PMID 30744161›Full record

ArticleMolecules (Basel, Switzerland)2019

Systematic Identification of Thiosemicarbazides for Inhibition of

Agata Paneth, Lidia Węglińska, Adrian Bekier, Edyta Stefaniszyn, Monika Wujec, Nazar Trotsko, Katarzyna Dzitko

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Transient Adaptation ofInternational journal of molecular sciences · 2024
    Article
  4. TZD-Based Hybrid Molecules Act as Dual Anti-International journal of molecular sciences · 2023
    Article
  5. Article
  6. Inhibition ofJournal of enzyme inhibition and medicinal chemistry · 2022
    Article
  7. Article
  8. Review
  9. Article
  10. 4-Arylthiosemicarbazide derivatives as a new class of tyrosinase inhibitors and anti-Journal of enzyme inhibition and medicinal chemistry · 2021
    Article
  11. Article
  12. Article
  13. Article
  14. Synthesis and In Vitro Anti-Molecules (Basel, Switzerland) · 2019
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Agata PanethDepartment of Organic Chemistry, Medical University, Chodźki 4a, 20-093 Lublin, Poland. agata.paneth@umlub.pl.ORCID 0000-0002-8198-7702
Lidia WęglińskaDepartment of Organic Chemistry, Medical University, Chodźki 4a, 20-093 Lublin, Poland. lidia.weglinska@umlub.pl.
Adrian BekierDepartment of Immunoparasitology, Faculty of Biology and Environmental Protection, University of Lodz, Banacha 12/16, 90-237 Lodz, Poland. adrian.bekier@unilodz.eu.
Edyta StefaniszynDepartment of Organic Chemistry, Medical University, Chodźki 4a, 20-093 Lublin, Poland. edyta.stefaniszyn@umlub.pl.
Monika WujecDepartment of Organic Chemistry, Medical University, Chodźki 4a, 20-093 Lublin, Poland. monika.wujec@umlub.pl.
Nazar TrotskoDepartment of Organic Chemistry, Medical University, Chodźki 4a, 20-093 Lublin, Poland. nazar.trotsko@umlub.pl.
Katarzyna DzitkoDepartment of Immunoparasitology, Faculty of Biology and Environmental Protection, University of Lodz, Banacha 12/16, 90-237 Lodz, Poland. katarzyna.dzitko@biol.uni.lodz.pl.
Medical University of Lublin · PLUniversity of Łódź · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the key stages in the development of new therapies in the treatment of toxoplasmosis is the identification of new non-toxic small molecules with high specificity to

Indexed as

Drug Evaluation, PreclinicalAnimalsAntiparasitic AgentsDose-Response Relationship, DrugHumansInhibitory Concentration 50Models, MolecularMolecular ConformationMolecular StructureParasitic Sensitivity TestsSemicarbazidesStructure-Activity RelationshipToxoplasmaToxoplasmosisAntiparasitic AgentsSemicarbazidesthiosemicarbazideanti-Toxoplasma gondii activitySAR analysisthiosemicarbazidestoxicity

Identifiers

PMID30744161
PMCPMC6384730
OpenAlexW2912054686

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.