Evidence map›Paper›PMID 30744131›Full record

ArticleBioengineering (Basel, Switzerland)2019

3D Printing for Bio-Synthetic Biliary Stents.

Christen J Boyer, Moheb Boktor, Hrishikesh Samant, Luke A White, Yuping Wang, David H Ballard, Robert C Huebert, Jennifer E Woerner, Ghali E Ghali, Jonathan S Alexander

Open access · goldAbstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. 3D printing in palliative medicine: systematic review.BMJ supportive & palliative care · 2024
    Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Efficacy of Biodegradable Polydioxanone and Polylactic Acid Braided Biodegradable Biliary Stents for the Management of Benign Biliary Strictures.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2021
    Article
  14. Review
  15. Article
  16. Article
  17. Autologous Adipose Tissue-Derived Mesenchymal Stem Cells Introduced by Biliary Stents or Local Immersion in Porcine Bile Duct Anastomoses.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2020
    Article
  18. Bioengineering Liver Transplantation.Bioengineering (Basel, Switzerland) · 2019
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Christen J BoyerMolecular and Cellular Physiology, Health Sciences Center, Louisiana State University, Shreveport, LA 71103, USA. cboye2@lsuhsc.edu.
Moheb BoktorGastroenterology and Hepatology, Health Sciences Center, Louisiana State University, Shreveport, LA 71103, USA. mbokto@lsuhsc.edu.
Hrishikesh SamantGastroenterology and Hepatology, Health Sciences Center, Louisiana State University, Shreveport, LA 71103, USA. hsaman@lsuhsc.edu.
Luke A WhiteMolecular and Cellular Physiology, Health Sciences Center, Louisiana State University, Shreveport, LA 71103, USA. lwhit9@lsuhsc.edu.
Yuping WangObstetrics and Gynecology, Health Sciences Center, Louisiana State University, Shreveport, LA 71103, USA. jwoern@lsuhsc.edu.
David H BallardMallinckrodt Institute of Radiology, School of Medicine, Washington University, St. Louis, MO 63110, USA. GGhali@lsuhsc.edu.
Robert C HuebertGastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, USA. YWang1@lsuhsc.edu.
Jennifer E WoernerOral and Maxillofacial Surgery, Health Sciences Center, Louisiana State University, Shreveport, LA 71103, USA. davidballard@wustl.edu.
Ghali E GhaliOral and Maxillofacial Surgery, Health Sciences Center, Louisiana State University, Shreveport, LA 71103, USA. Huebert.Robert@mayo.edu.
Jonathan S AlexanderMolecular and Cellular Physiology, Health Sciences Center, Louisiana State University, Shreveport, LA 71103, USA. jalexa@lsuhsc.edu.
Louisiana State University Health Sciences Center Shreveport · USMallinckrodt (United States) · USMayo Clinic in Arizona · US

Funding

Molecular Mechanisms of Cholestatic FibrogenesisR01DK117861 · NIDDK · MAYO CLINIC ROCHESTER · PI Robert Christian Huebert · 2019 to 2026
$2.8M
Training OPportunities in Translational Imaging Education and Research (TOP-TIER)T32EB021955 · NIBIB · WASHINGTON UNIVERSITY · PI Hongyu An, Joseph Edward Ippolito · 2017 to 2026
$2.4M
Epigenetic Regulation in Primary Sclerosing CholangitisR03DK113339 · NIDDK · MAYO CLINIC ROCHESTER · PI HUEBERT, ROBERT CHRISTIAN · 2018 to 2019
$159k
LSU Research and Technology Foundation - LIFT2 110351233ANIBIB NIH HHS T32 EB021955NIDDK NIH HHS R01 DK117861NIDDK NIH HHS R03 DK113339
6 · The paper itself

Abstract

Three-dimensional (3D) printing is an additive manufacturing method that holds great potential in a variety of future patient-specific medical technologies. This project validated a novel crosslinked polyvinyl alcohol (XL-PVA) 3D printed stent infused with collagen, human placental mesenchymal stem cells (PMSCs), and cholangiocytes. The biofabrication method in the present study examined 3D printing and collagen injection molding for rapid prototyping of customized living biliary stents with clinical applications in the setting of malignant and benign bile duct obstructions. XL-PVA stents showed hydrophilic swelling and addition of radiocontrast to the stent matrix improved radiographic opacity. Collagen loaded with PMSCs contracted tightly around hydrophilic stents and dense choloangiocyte coatings were verified through histology and fluorescence microscopy. It is anticipated that design elements used in these stents may enable appropriate stent placement, provide protection of the stent-stem cell matrix against bile constituents, and potentially limit biofilm development. Overall, this approach may allow physicians to create personalized bio-integrating stents for use in biliary procedures and lays a foundation for new patient-specific stent fabrication techniques.

Indexed as

3D printinghepatobiliary stentmedical devicepersonalized medicinestem cellstissue engineering

Identifiers

PMID30744131
PMCPMC6466390
OpenAlexW2913525706

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.