Evidence map›Paper›PMID 30744039›Full record

ArticleJournal of clinical medicine2019

Spirit-Quieting Traditional Chinese Medicine may Improve Survival in Prostate Cancer Patients with Depression.

Po-Hung Lin, Shun-Ku Lin, Ren-Jun Hsu, See-Tong Pang, Cheng-Keng Chuang, Ying-Hsu Chang, Jui-Ming Liu

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Po-Hung LinDivision of Urology, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan 333, Taiwan. m7587@adm.cgmh.org.tw.
Shun-Ku LinDepartment of Chinese medicine, Taipei City Hospital, Ren-Ai Branch, Taipei 106, Taiwan. gigilaskl@gmail.com.
Ren-Jun HsuGraduate Institute of Life Sciences, National Defense Medical Center, Taipei 114, Taiwan. hsurnai@gmail.com.
See-Tong PangDivision of Urology, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan 333, Taiwan. jacobpang@cloud.cgmh.org.tw.
Cheng-Keng ChuangDivision of Urology, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan 333, Taiwan. chuang89@cgmh.org.tw.
Ying-Hsu ChangDivision of Urology, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan 333, Taiwan. anatomy@cloud.cgmh.org.tw.
Jui-Ming LiuGraduate Institute of Life Sciences, National Defense Medical Center, Taipei 114, Taiwan. mento1218@gmail.com.
Chang Gung Memorial Hospital · TWNational Yang Ming Chiao Tung University · TWChang Gung University · TWTri-Service General Hospital · TW

Funding

Chang Gung Memorial Hospital Research Program (CMRP number CIRPD1D0032). CMRP number CIRPD1D0032).
6 · The paper itself

Abstract

Depression is associated with higher mortality in prostate cancer. However, whether traditional Chinese medicine (TCM) for depression improves outcomes in patients with prostate cancer is unclear. This retrospective cohort study evaluated the association between TCM for depression and mortality in patients with prostate cancer. During the period 1998⁻2012, a total of 248 prostate cancer patients in Taiwan with depression were enrolled and divided into three groups: TCM for depression (n = 81, 32.7%), TCM for other purposes (n = 53, 21.3%), and no TCM (n = 114, 46.0%). During a median follow-up of 6.2 years, 12 (14.8%), 13 (24.5%), and 36 (31.6%) deaths occurred in the TCM for depression, TCM for other purposes, and no TCM groups, respectively. After adjusting age at diagnosis, urbanization, insured amount, comorbidity disease, and prostate cancer type, TCM for depression was associated with a significantly lower risk of overall mortality based on a multivariate-adjusted Cox proportional-hazards model (hazard ratio 0.42, 95% confidence interval: 0.21⁻0.85, p = 0.02) and Kaplan⁻Meier survival curve (log-rank test, p = 0.0055) compared to no TCM. In conclusion, TCM for depression may have a positive association with the survival of prostate cancer patients with depression.

Indexed as

depressionprostate cancertraditional Chinese medicine

Identifiers

PMID30744039
PMCPMC6406565
OpenAlexW2913892527

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.