Evidence map›Paper›PMID 30744034›Full record

ArticleBrain sciences2019

Assessment and Management of HIV-Associated Cognitive Impairment: Experience from a Multidisciplinary Memory Service for People Living with HIV.

Kate Alford, Sube Banerjee, Eileen Nixon, Clara O'Brien, Olivia Pounds, Andrew Butler, Claire Elphick, Phillip Henshaw, Stuart Anderson, Jaime H Vera

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Brain sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05155787 (Construction and Evaluation of Neurofeedback Training), which is not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05155787 nacompletednot on this mapstarted 2021, after this paper: background citation

Construction and Evaluation of Neurofeedback Training (NFT) on Sleep Quality and Cognitive Function Performance Among HIV-infected Persons

TypeinterventionalSponsorNational Cheng-Kung University HospitalRan2021 to 2023Enrolled13ConditionsPoor Quality Sleep, HIV InfectionsArmsNeurofeedback, Shame neurofeedback
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
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  8. "A fog that impacts everything": a qualitative study of health-related quality of life in people living with HIV who have cognitive impairment.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Article
  9. Article
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  13. Review
  14. EEG event related potentials in sustained, focused and divided attention tasks: Potential biomarkers for cognitive impairment in HIV patients.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2021
    Article
  15. Article
  16. Risk Prediction in People Living With Human Immunodeficiency Virus: Are We Hitting the Target?Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
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  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Kate AlfordDepartment of Global Health and Infection, Brighton and Sussex Medical School, Brighton, BN1 9PX, UK. K.Alford@bsms.ac.uk.
Sube BanerjeeCentre for Dementia Studies, Brighton and Sussex Medical School, Brighton, BN1 9PX, UK. S.Banerjee@bsms.ac.uk.
Eileen NixonBrighton and Sussex University Hospitals NHS Trust, Brighton, BN2 1ES, UK. E.Nixon@bsuh.nhs.uk.
Clara O'BrienBrighton and Sussex University Hospitals NHS Trust, Brighton, BN2 1ES, UK. Clara.OBrien@bsuh.nhs.uk.
Olivia PoundsBrighton and Sussex University Hospitals NHS Trust, Brighton, BN2 1ES, UK. Olivia.Pounds@bsuh.nhs.uk.
Andrew ButlerDepartment of Medicine, Brighton and Sussex Medical School, Brighton, BN1 9PX, UK. Andrew.Butler@bsms.ac.uk.
Claire ElphickSussex Partnership NHS Foundation Trust, Worthing, BN13 3EP, UK. Claire.Elphick@sussexpartnership.nhs.uk.
Phillip HenshawSussex Partnership NHS Foundation Trust, Worthing, BN13 3EP, UK. Phillip.henshaw@sussexpartnership.nhs.uk.
Stuart AndersonBrighton and Sussex University Hospitals NHS Trust, Brighton, BN2 1ES, UK. Stuart.Anderson@bsuh.nhs.uk.
Jaime H VeraDepartment of Global Health and Infection, Brighton and Sussex Medical School, Brighton, BN1 9PX, UK. J.Vera@bsms.ac.uk.
Brighton and Sussex Medical School · GBUniversity Hospitals Sussex NHS Foundation Trust · GBSussex Partnership NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the HIV population ages, the prevalence of cognitive impairment (CI) is increasing, yet few services exist for the assessment and management of these individuals. Here we provide an initial description of a memory assessment service for people living with HIV and present data from a service evaluation undertaken in the clinic. We conducted an evaluation of the first 52 patients seen by the clinic. We present patient demographic data, assessment outcomes, diagnoses given and interventions delivered to those seen in the clinic. 41 patients (79%) of those seen in the clinic had objective CI: 16 (31%) met criteria for HIV-associated Neurocognitive Disorder (HAND), 2 (4%) were diagnosed with dementia, 14 (27%) showed CI associated with mental illness and/or drugs/alcohol, 7 (13%) had CI which was attributed to factors other than HIV and in 2 (4%) patients the cause remains unclear. 32 (62%) patients showed some abnormality on Magnetic Resonance Imaging (MRI) brain scans. Patients attending the clinic performed significantly worse than normative scores on all tests of global cognition and executive function. Interventions offered to patients included combination antiretroviral therapy modification, signposting to other services, case management, further health investigations and in-clinic advice. Our experience suggests that the need exists for specialist HIV memory services and that such a model of working can be successfully implemented into HIV patient care. Further work is needed on referral criteria and pathways. Diagnostic processes and treatment offered needs to consider and address the multifactorial aetiology of CI in HIV and this is essential for effective assessment and management.

Indexed as

cognitive impairmentHIVHIV-associated neurocognitive disorderpatient care

Identifiers

PMID30744034
PMCPMC6406482
OpenAlexW2913609279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.