Evidence map›Paper›PMID 30744023›Full record

ArticleInternational journal of molecular sciences2019

Biomimetic Surfaces Coated with Covalently Immobilized Collagen Type I: An X-Ray Photoelectron Spectroscopy, Atomic Force Microscopy, Micro-CT and Histomorphometrical Study in Rabbits.

Antonio Scarano, Felice Lorusso, Tiziana Orsini, Marco Morra, Giorgio Iviglia, Luca Valbonetti

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 43 citations in OpenAlex.

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  5. The dental implant surface: a review of the past, present and future.Journal of materials science. Materials in medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Antonio ScaranoDepartment of Medical, Oral and Biotechnological Sciences, Center for Research on Aging and Translational Medicine (CeSI-MeT), University of Chieti-Pescara, 66100 Chieti, Italy. ascarano@unich.it.ORCID 0000-0003-1374-6146
Felice LorussoDepartment of Medical, Oral and Biotechnological Sciences, Center for Research on Aging and Translational Medicine (CeSI-MeT), University of Chieti-Pescara, 66100 Chieti, Italy. drlorussofelice@gmail.com.ORCID 0000-0002-2660-9231
Tiziana OrsiniCNR-National Research Council, Institute of Cell Biology and Neurobiology (IBCN), 00015 Roma, Italy. tiziana.orsini@cnr.it.ORCID 0000-0003-0023-7916
Marco MorraNobil Bio Ricerche Srl, 14037 Portacomaro (AT), Italy. mmorra@nobilbio.it.
Giorgio IvigliaNobil Bio Ricerche Srl, 14037 Portacomaro (AT), Italy. giviglia@nobilbio.it.ORCID 0000-0003-1978-6501
Luca ValbonettiFaculty of Bioscience and Agro-Food and Environmental Technology, University of Teramo, 64100 Teramo, Italy. lvalbonetti@unite.it.ORCID 0000-0001-5914-615X
University of Chieti-Pescara · ITNational Research Council · ITPolitecnico di Torino · ITUniversity of Teramo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe process of osseointegration of dental implants is characterized by healing phenomena at the level of the interface between the surface and the bone. Implant surface modification has been introduced in order to increase the level of osseointegration. The purpose of this study is to evaluate the influence of biofunctional coatings for dental implants and the bone healing response in a rabbit model. The implant surface coated with collagen type I was analyzed through X-ray Photoelectron Spectroscopy (XPS), Atomic Force Microscopy (AFM), micro-CT and histologically.

methodsThe sandblasted and double acid etched surface coated with collagen type I, and uncoated sandblasted and double acid etched surface were evaluated by X-ray Photoelectron Spectroscopy (XPS) and Atomic Force Microscopy (AFM) analysis in order evaluate the different morphology. In vivo, a total of 36 implants were positioned in rabbit articular femoral knee-joint, 18 fixtures for each surface. Micro-CT scans, histological and histomorphometrical analysis were conducted at 15, 30 and 60 days.

resultsA histological statistical differences were evident at 15, 30 and 60 days (

conclusionHowever, the final results showed that a coating of collagen type I on the implant surface represents a promising procedure able to improve osseointegration, especially in regions with a low bone quality.

Indexed as

Biomimetic MaterialsBiomimeticsCoated Materials, BiocompatibleCollagen Type IAnimalsHistocytochemistryMicroscopy, Atomic ForcePhotoelectron SpectroscopyRabbitsSurface PropertiesTime FactorsX-Ray MicrotomographyCoated Materials, BiocompatibleCollagen Type Ibone implant contactcollagen type Ihydrophilic surfaceimplant surfacesmicro CT

Identifiers

PMID30744023
PMCPMC6387268
OpenAlexW2911722581

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.