Evidence map›Paper›PMID 30743265›Full record

ArticleAnnals of internal medicine2019

Fitness and Body Mass Index During Adolescence and Disability Later in Life: A Cohort Study.

Pontus Henriksson, Hanna Henriksson, Per Tynelius, Daniel Berglind, Marie Löf, I-Min Lee, Eric J Shiroma, Francisco B Ortega

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PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 68 citations in OpenAlex.

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  13. Role of Leptin in Obesity, Cardiovascular Disease, and Type 2 Diabetes.International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Pontus HenrikssonLinköping University, Linköping, Sweden; University of Granada, Granada, Spain; and Karolinska Institutet, Stockholm, Sweden (P.H.).
Hanna HenrikssonUniversity of Granada, Granada, Spain, and Linköping University, Linköping, Sweden (H.H.).
Per TyneliusKarolinska Institutet and Stockholm County Council, Stockholm, Sweden (P.T.).
Daniel BerglindKarolinska Institutet, Stockholm, Sweden (D.B.).
Marie LöfKarolinska Institutet, Stockholm, Sweden, and Linköping University, Linköping, Sweden (M.L.).
I-Min LeeBrigham and Women's Hospital, Harvard Medical School, and Harvard T.H. Chan School of Public Health, Boston, Massachusetts (I.L.).
Eric J ShiromaNational Institute on Aging, Bethesda, Maryland (E.J.S.).
Francisco B OrtegaUniversity of Granada, Granada, Spain, and Karolinska Institutet, Stockholm, Sweden (F.B.O.).
Karolinska Institutet · SEUniversidad de Granada · ESBrigham and Women's Hospital · USLinköping University · SENational Institute on Aging · US

Funding

Intramural NIH HHS Z99 AG999999
6 · The paper itself

Abstract

Background: Low physical fitness, obesity, and the combination of the two in adolescence may be related to risk for disability in adulthood, but this has rarely been studied. Objective: To examine individual and combined associations of cardiorespiratory fitness and obesity in male adolescents with later receipt of a disability pension due to all and specific causes. Design: Population-based cohort study. Setting: Sweden. Participants: 1 079 128 Swedish adolescents aged 16 to 19 years who were conscripted into the military between 1972 and 1994. Measurements: Cardiorespiratory fitness and body mass index (BMI) were measured at conscription and were related to information on later receipt of a disability pension obtained from the Social Insurance Agency. Results: Over a median follow-up of 28.3 years, 54 304 men were granted a disability pension. Low cardiorespiratory fitness was strongly associated with later receipt of a disability pension due to all causes (hazard ratio, 3.74 [95% CI, 3.55 to 3.95] for lowest vs. highest fitness decile) and specific causes (psychiatric, musculoskeletal, injuries, nervous system, circulatory, and tumors). Obesity was associated with greater risk for receipt of a disability pension due to all and specific causes, with the greatest risks observed for class II and III obesity. Compared with being unfit, being moderately or highly fit was associated with attenuated risk for receipt of a disability pension across BMI categories. Limitation: The cohort did not include women, had data on smoking and alcohol intake only in a subsample, and lacked repeated measures of exposures and covariates. Conclusion: Low cardiorespiratory fitness, obesity, and the combination of the two were strongly associated with later chronic disability due to a wide range of diseases and causes. Although additional well-designed studies are required, these findings support the importance of high cardiorespiratory fitness and healthy body weight during adolescence to prevent later chronic disease. Primary Funding Source: Karolinska Institutet.

Indexed as

Body Mass IndexCardiorespiratory FitnessDisability EvaluationAdolescentChronic DiseaseFollow-Up StudiesHumansMalePediatric ObesityPensionsProspective StudiesRisk FactorsSwedenYoung Adult

Identifiers

PMID30743265
PMCPMC6814012
OpenAlexW2914195914

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.