ArticlePLoS genetics2019
A genome-wide association study reveals a novel regulator of ovule number and fertility in Arabidopsis thaliana.
Article in PLoS genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 46 citations in OpenAlex.
- Co-identification of candidate regions associated with ovule number per ovary through QTL analysis and GWAS inBreeding science · 2025Article
- A high-density linkage map and fine QTL mapping of architecture, phenology, and yield-related traits in faba bean (Frontiers in plant science · 2025Article
- The Arabidopsis SNARE complex genes regulate the early stages of pollen-stigma interactions.Plant reproduction · 2024Article
- FLOWERING LOCUS T-mediated thermal signalling regulates age-dependent inflorescence development in Arabidopsis thaliana.Journal of experimental botany · 2024Article
- Article
- Dissection of the genetic basis and molecular mechanism of ovule number per ovary in oilseed rape (Frontiers in plant science · 2024Article
- Linkage and association mapping of ovule number per ovary (ON) in oilseed rape (Molecular breeding : new strategies in plant improvement · 2023Article
- The selfing syndrome and beyond: diverse evolutionary consequences of mating system transitions in plants.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- The genetic basis of natural variation in the timing of vegetative phase change in Arabidopsis thaliana.Development (Cambridge, England) · 2022Article
- Interspecific complementation-restoration of phenotype in Arabidopsis cuc2cuc3 mutant by sugarcane CUC2 gene.BMC plant biology · 2022Article
- CAND1 is required for pollen viability inFrontiers in plant science · 2022Article
- Genetic dissection of the natural variation of ovule number per ovary in oilseed rape germplasm (Frontiers in plant science · 2022Article
- Molecular Network for Regulation of Ovule Number in Plants.International journal of molecular sciences · 2021Review
- Advances and Challenges for QTL Analysis and GWAS in the Plant-Breeding of High-Yielding: A Focus on Rapeseed.Biomolecules · 2021Review
- The evolution and genetics of sexually dimorphic 'dual' mimicry in the butterflyProceedings. Biological sciences · 2021Article
- Genome-Wide Identification of Powdery Mildew Resistance in Common Bean (Frontiers in genetics · 2021Article
- Evolutionary Genomics of Plant Gametophytic Selection.Plant communications · 2020Review
- NERD1 is required for primexine formation and plasma membrane undulation during microsporogenesis inaBIOTECH · 2020Article
- Gynoecium size and ovule number are interconnected traits that impact seed yield.Journal of experimental botany · 2020Review
- Genome-Wide Association Analysis Identifies Candidate Genes Regulating Seed Number Per Silique inPlants (Basel, Switzerland) · 2020Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ovules contain the female gametophytes which are fertilized during pollination to initiate seed development. Thus, the number of ovules that are produced during flower development is an important determinant of seed crop yield and plant fitness. Mutants with pleiotropic effects on development often alter the number of ovules, but specific regulators of ovule number have been difficult to identify in traditional mutant screens. We used natural variation in Arabidopsis accessions to identify new genes involved in the regulation of ovule number. The ovule numbers per flower of 189 Arabidopsis accessions were determined and found to have broad phenotypic variation that ranged from 39 ovules to 84 ovules per pistil. Genome-Wide Association tests revealed several genomic regions that are associated with ovule number. T-DNA insertion lines in candidate genes from the most significantly associated loci were screened for ovule number phenotypes. The NEW ENHANCER of ROOT DWARFISM (NERD1) gene was found to have pleiotropic effects on plant fertility that include regulation of ovule number and both male and female gametophyte development. Overexpression of NERD1 increased ovule number per fruit in a background-dependent manner and more than doubled the total number of flowers produced in all backgrounds tested, indicating that manipulation of NERD1 levels can be used to increase plant productivity.
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