ArticlePLoS computational biology2019
Cell geometry determines symmetric and asymmetric division plane selection in Arabidopsis early embryos.
Article in PLoS computational biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Inferring cell division from cell shape.The Plant cell · 2026Article
- Temporal changes in surface tension guide microtubule organization and accurate asymmetric division of Arabidopsis zygotes.Nature communications · 2026Article
- Imaging and genetic toolbox to study Arabidopsis embryogenesis.The New phytologist · 2026Review
- KATANIN promotes cell elongation and division to generate proper cell numbers in maize organs.Nature communications · 2026Article
- Spiral phyllotaxis in the moss Physcomitrium patens emerges from simple division rules of the apical cell.Current biology : CB · 2026Article
- The actin cytoskeleton is required to maintain plant cell division orientation against cellular geometry.Science advances · 2026Article
- 3D geometry and mechanics of a single apical stem cell ensure helically symmetric plant body in multicellular models.Frontiers in plant science · 2026Article
- A transient radial cortical microtubule array primes cell division inProceedings of the National Academy of Sciences of the United States of America · 2024Article
- TreeJ: an ImageJ plugin for interactive cell lineage reconstruction from static images.Plant methods · 2023Article
- The shift to 3D growth during embryogenesis of kelp species, atlas of cell division and differentiation of Saccharina latissima.Development (Cambridge, England) · 2023Article
- Computer models of cell polarity establishment in plants.Plant physiology · 2023Review
- GRAS transcription factors regulate cell division planes in moss overriding the default rule.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Regulation of organelle size and organization during development.Seminars in cell & developmental biology · 2023Review
- Article
- Defects in division plane positioning in the root meristematic zone affect cell organization in the differentiation zone.Journal of cell science · 2022Article
- Division site determination during asymmetric cell division in plants.The Plant cell · 2022Review
- Cycling in a crowd: Coordination of plant cell division, growth, and cell fate.The Plant cell · 2022Review
- Auxin-dependent control of cytoskeleton and cell shape regulates division orientation in the Arabidopsis embryo.Current biology : CB · 2021Article
- Optimal BR signalling is required for adequate cell wall orientation in the Arabidopsis root meristem.Development (Cambridge, England) · 2021Article
- TheQuantitative plant biology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant tissue architecture and organ morphogenesis rely on the proper orientation of cell divisions. Previous attempts to predict division planes from cell geometry in plants mostly focused on 2D symmetric divisions. Using the stereotyped division patterns of Arabidopsis thaliana early embryogenesis, we investigated geometrical principles underlying plane selection in symmetric and in asymmetric divisions within complex 3D cell shapes. Introducing a 3D computational model of cell division, we show that area minimization constrained on passing through the cell centroid predicts observed divisions. Our results suggest that the positioning of division planes ensues from cell geometry and gives rise to spatially organized cell types with stereotyped shapes, thus underlining the role of self-organization in the developing architecture of the embryo. Our data further suggested the rule could be interpreted as surface minimization constrained by the nucleus position, which was validated using live imaging of cell divisions in the stomatal cell lineage.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.