ArticleAIDS education and prevention : official publication of the International Society for AIDS Education2019
Acceptability, Feasibility, and Preliminary Efficacy of a Theory-Based Relational Embodied Conversational Agent Mobile Phone Intervention to Promote HIV Medication Adherence in Young HIV-Positive African American MSM.
Article in AIDS education and prevention : official publication of the International Society for AIDS Education, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04217174 (A Mobile Phone Intervention Using a Relational Human Talking Avatar to Promote Multiple Stages of the HIV Care Continuum in African American MSM), which is not on this map. Cited by 37 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Mobile Phone Intervention Using a Relational Human Talking Avatar to Promote Multiple Stages of the HIV Care Continuum in African American MSM
Who cites it
37 citing papers in PubMed, 7 syntheses or guidelines pooled it, 64 citations in OpenAlex.
- Conversational Agents Supporting Self-Management in People With a Chronic Disease: Systematic Review.Journal of medical Internet research · 2025Pooled it
- A Systematic Review of Interventions for Young Men Who Have Sex With Men and Young Transgender Women Living with HIV.AIDS and behavior · 2024Pooled it
- mHealth-Based Gamification Interventions Among Men Who Have Sex With Men in the HIV Prevention and Care Continuum: Systematic Review and Meta-Analysis.JMIR mHealth and uHealth · 2024Pooled it
- Effectiveness and acceptability of conversational agents for sexual health promotion: a systematic review and meta-analysis.Sexual health · 2022Pooled it
- Behavioral Theories and Motivational Features Underlying eHealth Interventions for Adolescent Antiretroviral Adherence: Systematic Review.JMIR mHealth and uHealth · 2021Pooled it
- A systematic review of mHealth interventions for HIV prevention and treatment among gay, bisexual, and other men who have sex with men.Translational behavioral medicine · 2020Pooled it
- Computer-Controlled Virtual Humans in Patient-Facing Systems: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2020Pooled it
- A Randomized Controlled Trial of the My Personal Health Guide Mobile Phone App on ART Adherence Among Young African American Men Who Have Sex With Men Living With HIV in the United States.Open forum infectious diseases · 2026Trial
- Evidence of Efficacy of the My Personal Health Guide Mobile Phone App on Antiretroviral Therapy Adherence Among Young African American Men Who Have Sex With Men at 1 Month: Randomized Controlled Trial.JMIR mHealth and uHealth · 2026Trial
- Design and development of a mobile application for drug information and other health data for users and patients of pharmacies and outpatient pharmaceutical services.Exploratory research in clinical and social pharmacy · 2025Article
- Participatory Development and Concept Testing of mHealth Messaging to Support Care Engagement and Antiretroviral Therapy Adherence for Women Living With HIV in the Southern United States: Focus Group Study.JMIR formative research · 2025Article
- Implementation Strategies for Digital HIV Prevention and Care Interventions for Youth: A Scoping Review.Current HIV/AIDS reports · 2025Article
- e-Health applications for outpatient professional pharmaceutical care services: A scoping review.Exploratory research in clinical and social pharmacy · 2025Review
- Women Empowered to Connect With Addiction Resources and Engage in Evidence-Based Treatment (WE-CARE)-an mHealth Application for the Universal Screening of Alcohol, Substance Use, Depression, and Anxiety: Usability and Feasibility Study.JMIR formative research · 2025Article
- Formative research and design for a mobile health platform for oral cancer screening and detection (OC-DETECT)-a mixed methods study.Frontiers in digital health · 2025Article
- A multi-informant qualitative analysis of desired features for an mHealth tool for youth living with HIV in South Carolina.Journal of pediatric psychology · 2024Article
- Developing an mHealth program to improve HIV care continuum outcomes among young Black gay and bisexual men.BMC public health · 2024Article
- Development of a culturally targeted chatbot to inform living kidney donor candidates of African ancestry about APOL1 genetic testing: a mixed methods study.Journal of community genetics · 2024Article
- RACares: a conceptual design to guide mHealth relational agent development based on a systematic review.mHealth · 2024Review
- Virtual avatars as a new tool for human immunodeficiency virus prevention among men who have sex with men: a narrative review.mHealth · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
An embodied conversational agent can serve as a relational agent and provide information, motivation, and behavioral skills. To evaluate the feasibility, acceptability, and preliminary efficacy of My Personal Health Guide, a theory-based mobile-delivered embodied conversational agent intervention to improve adherence to antiretroviral therapy in young African American men who have sex with men, we conducted this prospective pilot study using a 3-month pre-post design. Outcome measures included adherence, acceptability, feasibility, pre versus post health literacy, and pre versus post self-efficacy. There were 43 participants. Pill count adherence > 80% improved from 62% at baseline to 88% at follow-up (p = .05). The acceptability of the app was high. Feasibility issues identified included loss of usage data from unplanned participant app deletion. Health literacy improved whereas self-efficacy was high at baseline and follow-up. This pilot study of My Personal Health Guide demonstrated acceptability and preliminary efficacy in improving adherence in this important population.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.