ReviewJournal of endocrinological investigation2019
Functional hypothalamic and drug-induced amenorrhea: an overview.
Review in Journal of endocrinological investigation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Endogenous transient doping: physical exercise acutely increases testosterone levels-results from a meta-analysis.Journal of endocrinological investigation · 2020Pooled it
- Fertility Beliefs and Menstrual Experiences Among Women Entering Opioid Use Disorder Treatment.Journal of addiction medicine · 2026Article
- [Endocrine genesis of the development of menstrual cycle disorders in reproductive age].Problemy endokrinologii · 2026Review
- Impact of psychological stress on ovarian function: Insights, mechanisms and intervention strategies (Review).International journal of molecular medicine · 2025Review
- Menstrual disturbances in women with advanced heart failure and heart transplant recipients.Frontiers in cardiovascular medicine · 2025Article
- Neuroendocrine disturbances in women with functional hypothalamic amenorrhea: an update and future directions.Endocrine · 2024Review
- Amenorrhea in an Adolescent Female as a Rare Adverse Event of Upadacitinib Treatment for Atopic Dermatitis.Patient preference and adherence · 2024Article
- Lithium Induced Amenorrhea: A First Case Report.Acta medica Lituanic · 2024Article
- Dose-response association between 24-hour total movement activity and testosterone deficiency in adult males.Frontiers in endocrinology · 2023Article
- Cognition, Behavior, Sexuality, and Autonomic Responses of Women with Hypothalamic Amenorrhea.Brain sciences · 2022Article
- Sports and the menstrual cycle.Case reports in women's health · 2022Article
- Has Menstruation Disappeared? Functional Hypothalamic Amenorrhea-What Is This Story about?Nutrients · 2021Review
- Mechanisms of Central Hypogonadism.International journal of molecular sciences · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFunctional hypothalamic amenorrhea (FHA) is a form of chronic anovulation not due to identifiable organic causes and with adverse health consequences. The identification of women with this disorder or the precocious identification of women at risk is based on the knowledge of lifestyle risk factors or behaviors such as stress, weight loss, and excessive physical exercise that are known to negatively impact gonadal axis activity.
methodsIn this overview, we described the most common forms of FHA, in particular stress-induced amenorrhea and overtraining-induced amenorrhea. In addition, although its mechanisms can differ from those involved in FHA, we reviewed the available literature on drug-induced amenorrhea, highlighting the clear connection between this condition and psychoactive drugs such as antipsychotics, antidepressants and anti-epilectics thus raising concern about the role that the abuse of substances such as opioids or alcohol can possibly have on the growing unexplained infertility of the female population.
Indexed as
Identifiers
30742257What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.