Evidence map›Paper›PMID 30742068›Full record

ArticleNature microbiology2019

Utilization of selenocysteine in early-branching fungal phyla.

Marco Mariotti, Gustavo Salinas, Toni Gabaldón, Vadim N Gladyshev

Open access · greenAbstract read
In one paragraph

Article in Nature microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 63 citations in OpenAlex.

  1. The Origin and Early Evolution of Fungi: Challenges, Inferences, and Principles.Annual review of cell and developmental biology · 2026
    Review
  2. Review
  3. Article
  4. An atlas of plant selenium metabolism.The New phytologist · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Absence of farnesol salvage inApplied and environmental microbiology · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. The geneFrontiers in microbiology · 2024
    Article
  13. Review
  14. Tuning tRNAs for improved translation.Frontiers in genetics · 2024
    Review
  15. Biosynthesis, Engineering, and Delivery of Selenoproteins.International journal of molecular sciences · 2023
    Review
  16. Recoding UAG to selenocysteine inRNA (New York, N.Y.) · 2023
    Article
  17. Review
  18. Article
  19. Article
  20. Diploid-dominant life cycles characterize the early evolution of Fungi.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Marco MariottiDivision of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. mmariotti@bwh.harvard.edu.ORCID http://orcid.org/0000-0002-7411-4161
Gustavo SalinasDepartamento de Biociencias, Facultad de Química, Universidad de la República, Montevideo, Uruguay.
Toni GabaldónBioinformatics and Genomics Programme, Centre for Genomic Regulation, Barcelona Institute of Science and Technology, Barcelona, Spain.
Vadim N GladyshevDivision of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. vgladyshev@rics.bwh.harvard.edu.
Brigham and Women's Hospital · USInstitució Catalana de Recerca i Estudis Avançats · ESUniversidad de la República de Uruguay · UY

Funding

Methionine sulfoxide reduction, selenium and agingR01AG021518 · NIA · UNIVERSITY OF NEBRASKA LINCOLN · PI GLADYSHEV, VADIM N. · 2003 to 2018
$5.0M
Selenoproteins as Targets for Cancer PreventionR01CA080946 · NCI · UNIVERSITY OF NEBRASKA LINCOLN · PI GLADYSHEV, VADIM N. · 2001 to 2018
$4.5M
Systems level understanding of selenoprotein biosynthesisR01DK117149 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI GLADYSHEV, VADIM N. · 2018 to 2022
$2.4M
NCI NIH HHS R01 CA080946NIA NIH HHS R01 AG021518NIDDK NIH HHS R01 DK117149
6 · The paper itself

Abstract

Selenoproteins are a diverse group of proteins containing selenocysteine (Sec)-the twenty-first amino acid-incorporated during translation via a unique recoding mechanism

Indexed as

Fungal ProteinsFungiPhylogenySelenocysteineSelenoproteinsFungal ProteinsSelenocysteineSelenoproteins

Identifiers

PMID30742068
PMCPMC6551623
OpenAlexW2914919691

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.