Evidence map›Paper›PMID 30741971›Full record

ArticleScientific reports2019

Enantiomeric Isoflavones with neuroprotective activities from the Fruits of Maclura tricuspidata.

Nguyen Tuan Hiep, Jaeyoung Kwon, Sungeun Hong, Nahyun Kim, Yuanqiang Guo, Bang Yeon Hwang, Woongchon Mar, Dongho Lee

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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  8. Anti-Metastatic Effect of Gold Nanoparticle-ConjugatedInternational journal of nanomedicine · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 3 countries.

Nguyen Tuan HiepDepartment of Biosystems and Biotechnology, College of Life Science and Biotechnology, Korea University, Seoul, 02841, Republic of Korea.
Jaeyoung KwonNatural Constituents Research Center, Korea Institute of Science and Technology (KIST), Gangneung, 25451, Republic of Korea.
Sungeun HongNatural Products Research Institute, College of Pharmacy, Seoul National University, Seoul, 151-742, Republic of Korea.
Nahyun KimForest Medicinal Resources Research Center, National Institute of Forest Science, Yeongju, 36040, Republic of Korea.
Yuanqiang GuoState Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, 300350, People's Republic of China.
Bang Yeon HwangCollege of Pharmacy, Chungbuk National University, Cheongju, 361-763, Republic of Korea.
Woongchon MarNatural Products Research Institute, College of Pharmacy, Seoul National University, Seoul, 151-742, Republic of Korea. mars@snu.ac.kr.
Dongho LeeDepartment of Biosystems and Biotechnology, College of Life Science and Biotechnology, Korea University, Seoul, 02841, Republic of Korea. dongholee@korea.ac.kr.
Seoul National University · KRChungbuk National University · KRKorea Forest Service · KRKorea Institute of Science and Technology · KRKorea University · KRNankai University · CNNational Library of Vietnam · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Seven pairs of enantiomeric isoflavones (1a/1b-7a/7b) were obtained from the ethyl acetate extract of the fruits of Maclura tricuspidata (syn. Cudrania tricuspidata), and successfully separated by chiral high-pressure liquid chromatography (HPLC). The structures and absolute configurations of the enantiomeric isoflavones were established on the basic of comprehensive spectroscopic analyses and quantum chemical calculation methods. Compounds 1, 1a, and 1b exhibited neuroprotective activities against oxygen-glucose deprivation/reoxygenation (ODG/R)-induced SH-SY5Y cells death with EC

Indexed as

Cell DeathCell Line, TumorFruitHumansIsoflavonesMacluraMagnetic Resonance SpectroscopyMolecular StructureNeuroprotectionNeuroprotective AgentsPhytochemicalsPlant ExtractsReactive Oxygen SpeciesSignal TransductionIsoflavonesNeuroprotective AgentsPhytochemicalsPlant ExtractsReactive Oxygen Species

Identifiers

PMID30741971
PMCPMC6370789
OpenAlexW2914111893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.