ArticleNature communications2019
Correspondence between cerebral glucose metabolism and BOLD reveals relative power and cost in human brain.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.
What it found
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Who cites it
64 citing papers in PubMed, 99 citations in OpenAlex.
- Disrupted metabolic connectivity in dopaminergic and cholinergic networks at different stages of dementia fromScientific reports · 2021Trial
- Baseline electrophysiology versus oxidative metabolism as traits of inter-network differences in neurometabolic association.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026Article
- Timing and Duration of Prediabetic Metabolic Dysfunction Differentially Impact Cerebral Perfusion, Vascular Structure, and Behavior.Journal of cardiovascular translational research · 2026Article
- Article
- Synaptic density imaging in behavioral variant frontotemporal dementia: A comparison ofAlzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Energetic implications of fMRI-based nodal complex network metrics: a complex picture unfolds across diverse brain states.bioRxiv : the preprint server for biology · 2026Article
- Age-related changes to brain energetics revealed by PET/MRI imaging.NeuroImage. Clinical · 2026Article
- PET in conjunction with resting-state functional MRI for the study of chronic disorders of consciousness.Brain communications · 2026Article
- Disrupted Coupling Between Cerebral Glucose Metabolism and Intrinsic Functional Connectivity: A Hybrid PET/fMRI Study on Frontotemporal Dementia.Human brain mapping · 2025Article
- The expression of insulin signaling and N-methyl-D-aspartate receptor genes in areas of gray matter atrophy is associated with cognitive function in type 2 diabetes.Journal of Alzheimer's disease : JAD · 2025Article
- Early Brain Functional Connectivity Changes Induced by Antidepressants and Placebo.bioRxiv : the preprint server for biology · 2025Article
- Age-related changes of human brain metabolism.European journal of nuclear medicine and molecular imaging · 2025Article
- Natural trajectory subclasses of cognitive impairment in breast cancer patients experiencing insomnia.Cancer · 2025Article
- The link to steady-state oxidative metabolism and hemodynamics varies across rs-fMRI metrics: A whole-brain assessment using macrovascular correction.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Altered neurovascular coupling and structure-function coupling in Moyamoya disease affect postoperative collateral formation.Scientific reports · 2024Article
- Estimating the energy of dissipative neural systems.Cognitive neurodynamics · 2024Article
- Spatiotemporal cerebral blood flow dynamics underlies emergence of the limbic-sensorimotor-association cortical gradient in human infancy.Nature communications · 2024Article
- Impaired brain glucose metabolism in glucagon-like peptide-1 receptor knockout mice.Nutrition & diabetes · 2024Article
- Altered functional brain connectivity, efficiency, and information flow associated with brain fog after mild to moderate COVID-19 infection.Scientific reports · 2024Article
- Spatiotemporal cerebral blood flow dynamics underlies emergence of the limbic-sensorimotor-association cortical gradient in human infancy.Research square · 2024Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
The correspondence between cerebral glucose metabolism (indexing energy utilization) and synchronous fluctuations in blood oxygenation (indexing neuronal activity) is relevant for neuronal specialization and is affected by brain disorders. Here, we define novel measures of relative power (rPWR, extent of concurrent energy utilization and activity) and relative cost (rCST, extent that energy utilization exceeds activity), derived from FDG-PET and fMRI. We show that resting-state networks have distinct energetic signatures and that brain could be classified into major bilateral segments based on rPWR and rCST. While medial-visual and default-mode networks have the highest rPWR, frontoparietal networks have the highest rCST. rPWR and rCST estimates are generalizable to other indexes of energy supply and neuronal activity, and are sensitive to neurocognitive effects of acute and chronic alcohol exposure. rPWR and rCST are informative metrics for characterizing brain pathology and alternative energy use, and may provide new multimodal biomarkers of neuropsychiatric disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.