ArticleNature communications2019
N-formyl-stabilizing quasi-catalytic species afford rapid and selective solvent-free amination of biomass-derived feedstocks.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 89 citations in OpenAlex.
- Synthesis of Primary Amines via Reductive Amination of Aldehydes and Ketones Over a Ni-Doped MFM-300(Cr) Catalyst.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Simple Cobalt Nanoparticle-Catalyzed Reductive Amination for Selective Synthesis of a Broad Range of Primary Amines.Molecules (Basel, Switzerland) · 2025Article
- Furan Distribution as a Severity Indicator upon Organosolv Fractionation of Hardwood Sawdust through a Novel Ternary Solvent System.ACS sustainable chemistry & engineering · 2024Article
- Synthesis and characterization of PdHeliyon · 2023Article
- An efficient approach for the green synthesis of biologically active 2,3-dihydroquinazolin-4(1RSC advances · 2023Article
- Nanoparticles and single atoms of cobalt synergistically enabled low-temperature reductive amination of carbonyl compounds.Chemical science · 2022Article
- Research Progress on the Photo-Driven Catalytic Production of Biodiesel.Frontiers in chemistry · 2022Review
- Oxidative C-C bond cleavage of ligninFrontiers in chemistry · 2022Review
- Cascade Upgrading of Biomass-Derived Furfural to γ-Valerolactone Over Zr/Hf-Based Catalysts.Frontiers in chemistry · 2022Review
- Editorial: Sustainable catalytic production of bio-based heteroatom-containing compounds - volume II.Frontiers in chemistry · 2022Article
- Sustainable Approaches to Selective Conversion of Cellulose Into 5-Hydroxymethylfurfural Promoted by Heterogeneous Acid Catalysts: A Review.Frontiers in chemistry · 2022Review
- The Increasing Value of Biomass: Moving From C6 Carbohydrates to Multifunctionalized Building Blocks via 5-(hydroxymethyl)furfural.ChemistryOpen · 2020Review
- Visible-light-driven amino acids production from biomass-based feedstocks over ultrathin CdS nanosheets.Nature communications · 2020Article
- A Facile Direct Route to N-(Un)substituted Lactams by Cycloamination of Oxocarboxylic Acids without External Hydrogen.ChemSusChem · 2019Article
- Efficient Transfer Hydrogenation of Nitro Compounds to Amines Enabled by Mesoporous N-Stabilized Co-Zn/C.Frontiers in chemistry · 2019Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nitrogen-containing compounds, especially primary amines, are vital building blocks in nature and industry. Herein, a protocol is developed that shows in situ formed N-formyl quasi-catalytic species afford highly selective synthesis of formamides or amines with controllable levels from a variety of aldehyde- and ketone-derived platform chemical substrates under solvent-free conditions. Up to 99% yields of mono-substituted formamides are obtained in 3 min. The C-N bond formation and N-formyl species are prevalent in the cascade reaction sequence. Kinetic and isotope labeling experiments explicitly demonstrate that the C-N bond is activated for subsequent hydrogenation, in which formic acid acts as acid catalyst, hydrogen donor and as N-formyl species source that stabilize amine intermediates elucidated with density functional theory. The protocol provides access to imides from aldehydes, ketones, carboxylic acids, and mixed-substrates, requires no special catalysts, solvents or techniques and provides new avenues for amination chemistry.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.