Evidence map›Paper›PMID 30741631›Full record

ArticleeLife2019

Electron cryo-tomography provides insight into procentriole architecture and assembly mechanism.

Sam Li, Jose-Jesus Fernandez, Wallace F Marshall, David A Agard

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 51 citations in OpenAlex.

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  16. Basal bodies bend in response to ciliary forces.Molecular biology of the cell · 2022
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  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Sam LiDepartment of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, United States.ORCID 0000-0002-0210-8192
Jose-Jesus FernandezCentro Nacional de Biotecnologia (CSIC), Madrid, Spain.ORCID 0000-0003-2222-3355
Wallace F MarshallDepartment of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, United States.ORCID 0000-0002-8467-5763
David A AgardDepartment of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, United States.ORCID 0000-0003-3512-695X
University of California, San Francisco · USCentro Nacional de Biotecnología · ESHoward Hughes Medical Institute · US

Funding

The Yeast Centrosome - Structure Assembly & FunctionP01GM105537 · NIGMS · UNIVERSITY OF COLORADO · PI DAVIS, TRISHA N. · 2014 to 2018
$8.3M
Microtubule Nucleation: Structure & MechanismR01GM031627 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AGARD, DAVID A. · 1985 to 2016
$6.1M
Structure & Mechanism: microtubule nucleation, centrosomes, phage cytoskeletonR35GM118099 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AGARD, DAVID A. · 2016 to 2022
$3.6M
Pattern formation and regeneration in a single cellR01GM113602 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MARSHALL, WALLACE · 2015 to 2018
$1.6M
NIGMS NIH HHS P01 GM105537NIGMS NIH HHS R01 GM031627NIGMS NIH HHS R01 GM113602NIGMS NIH HHS R35 GM118099NIH HHS GM031627NIH HHS GM113602NIH HHS GM118099NIH HHS PO1 GM105537Spanish AEI/FEDER SAF2017-84565-R
6 · The paper itself

Abstract

Centriole is an essential structure with multiple functions in cellular processes. Centriole biogenesis and homeostasis is tightly regulated. Using electron cryo-tomography (cryoET) we present the structure of procentrioles from

Indexed as

Cryoelectron MicroscopyElectron Microscope TomographyCell CycleCell Cycle ProteinsCentriolesChlamydomonas reinhardtiiMicrotubulesCell Cycle Proteinscell biologycentriolechlamydomonas reinhardtiielectron cryo-tomographymicrotubule tripletprocentriolestructure heterogeneitysubtomogram averaging

Identifiers

PMID30741631
PMCPMC6384029
OpenAlexW2949579777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.