Evidence map›Paper›PMID 30741601›Full record

ArticleCell cycle (Georgetown, Tex.)2019

Human NOC3 is essential for DNA replication licensing in human cells.

Man-Hei Cheung, Aftab Amin, Rentian Wu, Yan Qin, Lan Zou, Zhiling Yu, Chun Liang

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. ThePharmaceuticals (Basel, Switzerland) · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Man-Hei Cheunga Division of Life Science, Center for Cancer Research and State Key Lab for Molecular Neuroscience , Hong Kong University of Science and Technology , Hong Kong , China.ORCID 0000-0002-4383-7666
Aftab Amina Division of Life Science, Center for Cancer Research and State Key Lab for Molecular Neuroscience , Hong Kong University of Science and Technology , Hong Kong , China.ORCID 0000-0003-3285-3422
Rentian Wua Division of Life Science, Center for Cancer Research and State Key Lab for Molecular Neuroscience , Hong Kong University of Science and Technology , Hong Kong , China.ORCID 0000-0003-3862-6394
Yan Qina Division of Life Science, Center for Cancer Research and State Key Lab for Molecular Neuroscience , Hong Kong University of Science and Technology , Hong Kong , China.
Lan Zoua Division of Life Science, Center for Cancer Research and State Key Lab for Molecular Neuroscience , Hong Kong University of Science and Technology , Hong Kong , China.
Zhiling Yud School of Chinese Medicine , Hong Kong Baptist University , Hong Kong , China.
Chun Lianga Division of Life Science, Center for Cancer Research and State Key Lab for Molecular Neuroscience , Hong Kong University of Science and Technology , Hong Kong , China.
Hong Kong University of Science and Technology · HKHong Kong Baptist University · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Noc3p (Nucleolar Complex-associated protein) is an essential protein in budding yeast DNA replication licensing. Noc3p mediates the loading of Cdc6p and MCM proteins onto replication origins during the M-to-G

Indexed as

DNA ReplicationAdaptor Proteins, Signal TransducingApoptosisBasic-Leucine Zipper Transcription FactorsCell Cycle ProteinsChromatinHeLa CellsHumansNuclear ProteinsProtein BindingReplication OriginRibosomesRNA InterferenceRNA, Small InterferingS Phase Cell Cycle CheckpointsTwo-Hybrid System TechniquesAdaptor Proteins, Signal TransducingBasic-Leucine Zipper Transcription FactorsCDC6 protein, humanCell Cycle ProteinsChromatinMCMBP protein, humanNOC3L protein, humanNuclear ProteinsRNA, Small InterferingDNA replicationFAD24NOC3Pre-RCreplication licensing

Identifiers

PMID30741601
PMCPMC6464578
OpenAlexW2912056503

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.