Evidence map›Paper›PMID 30741418›Full record

ReviewBritish journal of pharmacology2020

Histamine in the kidneys: what is its role in renal pathophysiology?

Cristina Grange, Maura Gurrieri, Roberta Verta, Roberto Fantozzi, Alessandro Pini, Arianna Carolina Rosa

Open access · greenAbstract readReview
In one paragraph

Review in British journal of pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Histamine regulates the activity and the expression of the NaInflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Function and Role of Histamine HPharmaceuticals (Basel, Switzerland) · 2023
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Histamine provides an original vista on cardiorenal syndrome.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  16. Review
  17. Article
  18. Effect of Bilastine on Diabetic Nephropathy in DBA2/J Mice.International journal of molecular sciences · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Cristina GrangeDepartment of Drug Science and Technology, University of Turin, Turin, Italy.ORCID 0000-0002-6960-5476
Maura GurrieriDepartment of Pharmaceutical Science and Technology, University of Turin, Turin, Italy.
Roberta VertaDepartment of Pharmaceutical Science and Technology, University of Turin, Turin, Italy.
Roberto FantozziDepartment of Pharmaceutical Science and Technology, University of Turin, Turin, Italy.ORCID 0000-0003-1129-2021
Alessandro PiniDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.ORCID 0000-0001-9828-2082
Arianna Carolina RosaDepartment of Pharmaceutical Science and Technology, University of Turin, Turin, Italy.ORCID 0000-0002-6139-9241
University of Turin · ITUniversity of Florence · IT

Funding

Università degli Studi di Torino
6 · The paper itself

Abstract

Starting with a role for histamine role in renal haemodynamics, evidence has accumulated, over time, suggesting a wider range of actions on renal function and this has renewed interest in the pathophysiological role of histamine in the kidney. Here we provide an up-to-date review of this topic. As the kidney expresses enzymes that synthesize and metabolise histamine, along with its receptors, all the components for histaminergic transmission are present in this tissue. The distribution of histamine receptors matches a wide range of effects. We address the questions of the redundancy of H

Indexed as

HistamineReceptors, HistamineAnimalsHemodynamicsHumansKidneyHistamineReceptors, Histamine

Identifiers

PMID30741418
PMCPMC7012958
OpenAlexW2912404235

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.