Evidence map›Paper›PMID 30741397›Full record

ArticleAIDS and behavior2019

If You Build It, Will They Use It? Preferences for Antiretroviral Therapy (ART) Adherence Monitoring Among People Who Inject Drugs (PWID) in Kazakhstan.

Alissa Davis, Lyailya Sarsembayeva, Valeriy Gulyaev, Sholpan Primbetova, Assel Terlikbayeva, Gaukhar Mergenova, Robert H Remien

Abstract read
In one paragraph

Article in AIDS and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alissa DavisSchool of Social Work, Columbia University, 1255 Amsterdam Avenue, Rm. 706, New York, NY, 10027, USA. ad3324@columbia.edu.ORCID http://orcid.org/0000-0003-2084-9741
Lyailya SarsembayevaColumbia University Global Health Research Center of Central Asia, Almaty, Kazakhstan.
Valeriy GulyaevColumbia University Global Health Research Center of Central Asia, Almaty, Kazakhstan.
Sholpan PrimbetovaColumbia University Global Health Research Center of Central Asia, Almaty, Kazakhstan.
Assel TerlikbayevaColumbia University Global Health Research Center of Central Asia, Almaty, Kazakhstan.
Gaukhar MergenovaColumbia University Global Health Research Center of Central Asia, Almaty, Kazakhstan.
Robert H RemienDivision of Gender, Sexuality & Health, HIV Center, New York State Psychiatric Institute, Columbia University Medical Center, New York, NY, USA.

Funding

The Statistics, Data Science, and Data Management (SDM) CoreP30MH043520 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI Claude Ann Mellins · 2003 to 2026
$48.2M
INSPIRE : Interdisciplinary Social and Behavioral Science Prevention and Intervention REsearch in HIVT32MH019139 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Claude Ann Mellins, Jae M. Sevelius · 1989 to 2026
$10.8M
A couple-based antiretroviral therapy adherence intervention for people who inject drugs in KazakhstanK01DA044853 · NIDA · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI DAVIS, ALISSA · 2018 to 2022
$903k
NIDA NIH HHS K01 DA044853NIDA NIH HHS K01DA044853-01A1NIMHD NIH HHS L60 MD010932NIMH NIH HHS P30 MH043520NIMH NIH HHS P30MH043520NIMH NIH HHS T32 MH019139NIMH NIH HHS T32MH019139
6 · The paper itself

Abstract

Adherence to antiretroviral therapy (ART) is an important predictor of long-term treatment success and is associated with optimal individual and public health outcomes. Novel technologies, such as electronic monitoring devices (EMDs) or pharmacokinetic testing, provide more objective measures of ART adherence than traditional measures of adherence (e.g., self-report) and may facilitate improved adherence through the provision of patient feedback. This study examines preferences for ART adherence monitoring among people who inject drugs (PWID) in Kazakhstan. In-depth interviews were conducted with 20 HIV-positive PWID, 18 of their intimate partners, and 7 AIDS Center healthcare providers in Almaty, Kazakhstan. Results indicated that patients varied in their preferences of which strategies would be most effective and acceptable to use in monitoring their adherence. Overall, patients were highly enthusiastic about the potential use of pharmacokinetic testing. Many participants supported the use of EMDs, though some were concerned about having their adherence tracked. Other participants thought reminders through text messaging or smart phone applications would be helpful, though several had concerns about confidentiality and others worried about technological difficulties operating a smart phone. Future studies should evaluate the feasibility and impact of providing quantitative drug levels as feedback for ART adherence using biomarkers of longer-term ART exposure, (i.e., hair sampling or dried blood spot testing).

Indexed as

Antiretroviral Therapy, Highly ActivePatient PreferenceAdultAnti-Retroviral AgentsDrug UsersFemaleHealth PersonnelHIV InfectionsHIV SeropositivityHumansInterviews as TopicKazakhstanMaleMedication AdherencePatient Acceptance of Health CarePersonalityAnti-Retroviral AgentsAntiretroviral therapy adherenceDrug monitoringKazakhstanPeople who inject drugs

Identifiers

PMID30741397
PMCPMC6689452

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.