ArticleExperimental brain research2019
The influence of microgravity on cerebral blood flow and electrocortical activity.
Article in Experimental brain research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 42 citations in OpenAlex.
- Neurophysiological markers of cognitive workload under altered gravity conditions using a gamified dual-task paradigm.Scientific reports · 2026Article
- Effects of seasonal factors on brain function: Systematic review and future perspectives.iScience · 2025Article
- A systematic review of the cerebrovascular adaptations following exposure to spaceflight or ground-based analogs: lessons from human and animal studies.NPJ microgravity · 2025Article
- Effect of simulated microgravity via head-down tilt on intracranial compliance, brain oscillations and cardiovascular autonomic modulation.Scientific reports · 2025Article
- Review of microgravity's impact on cardiovascular and nervous systems in space exploration.NPJ microgravity · 2025Review
- Heterogeneous and lateralized cervical vascular responses to a 7-day head-down tilt bed rest.NPJ microgravity · 2025Article
- Shades of gravity - effects of planetary gravity levels on electrocortical activity and neurocognitive performance.Brain structure & function · 2024Article
- Modelling large scale artery haemodynamics from the heart to the eye in response to simulated microgravity.NPJ microgravity · 2024Article
- Under pressure-the influence of hypergravity on electrocortical activity and neurocognitive performance.Experimental brain research · 2023Article
- Monitoring the Impact of Spaceflight on the Human Brain.Life (Basel, Switzerland) · 2022Review
- Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation.Physiological reviews · 2021Review
- Alterations in Cerebral Hemodynamics During Microgravity: A Literature Review.Medical science monitor : international medical journal of experimental and clinical research · 2021Review
- Head-Down Tilt Position, but Not the Duration of Bed Rest Affects Resting State Electrocortical Activity.Frontiers in physiology · 2021Article
- Spatial Updating Depends on Gravity.Frontiers in neural circuits · 2020Article
- Comprehensive Analysis of Macrocirculation and Microcirculation in Microgravity During Parabolic Flights.Frontiers in physiology · 2020Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 4 countries.
Funding
Abstract
Changes in gravity conditions have previously been reported to influence brain hemodynamics as well as neuronal activity. This paper attempts to identify a possible link between changes in brain blood flow and neuronal activity during microgravity. Middle cerebral artery flow velocity (MCAv) was measured using Doppler ultrasound. Brain cortical activity (i.e., cortical current density) was measured using electroencephalography. Finger blood pressure was recorded and exported to generate beat-by-beat systolic (SBP), diastolic (DBP) and mean arterial pressure (MAP), heart rate (HR), cardiac output (CO), and cerebrovascular conductance index (CVCi). Seventeen participants were evaluated under normal gravity conditions and microgravity conditions, during 15 bouts of 22-s intervals of weightlessness during a parabolic flight. Although MAP decreased and CO increased, MCAv remained unchanged in the microgravity condition. CVCi as the quotient of MCAv and MAP increased in microgravity. Cortical current density showed a global decrease. Our data support earlier data reporting a decrease in the amplitude of event-related potentials recorded during microgravity. However, the general decrease in neural excitability in microgravity seems not to be dependent on hemodynamic changes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.