ArticleeLife2019
A causal role for the precuneus in network-wide theta and gamma oscillatory activity during complex memory retrieval.
Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06284720 (Transcranial Alternating Current Stimulation for the Improvement of Episodic Memory in Healthy Older Adults), which is not on this map. Cited by 46 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Transcranial Alternating Current Stimulation for the Improvement of Episodic Memory in Healthy Older Adults
Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of acupuncture on the brain in primary insomnia: a coordinate-based meta-analysis of fMRI studies.Frontiers in neurology · 2023Pooled it
- Neural population dynamics and temporal context cells in macaque medial parietal cortex support temporal order memory.PLoS biology · 2026Article
- Switching on the behavioral and neural rhythmicity to retrieve memories when the number of retained items exceeds four.Scientific reports · 2026Article
- Magnetic NeuroRing: a portable adaptive brain-computer interface for real-time transcranial magnetic stimulation in post-stroke motor rehabilitation.npj biomedical innovations · 2026Article
- Improved autobiographical memory with central thalamic deep brain stimulation in traumatic brain injury.Brain communications · 2026Article
- Neural correlates and reinstatement of recent and remote memory in children and young adults.eLife · 2025Article
- Sex difference in neural substrates linking negative body image and disordered eating behaviors.Brain structure & function · 2025Article
- Dual transcranial electromagnetic stimulation of the precuneus boosts human long-term memory.eLife · 2025Article
- Electrophysiological Correlates of Lucid Dreaming: Sensor and Source Level Signatures.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Cross-frequency coupling patterns during oddball processing in disorders of consciousness: a delta-gamma predominance.Frontiers in psychology · 2025Article
- Precuneus activation correlates with the vividness of dynamic and static imagery: an fMRI study.Frontiers in human neuroscience · 2025Article
- Mapping the brain's fatigue network: a transdiagnostic systematic review and meta-analysis on functional correlates of mental fatigue.Brain communications · 2025Review
- Differential online and offline effects of theta-tACS on memory encoding and retrieval.Cognitive, affective & behavioral neuroscience · 2024Article
- Cross-regional coordination of activity in the human brain during autobiographical self-referential processing.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Treatment of Posttraumatic Stress Disorder: A State-of-the-art Review.Current neuropharmacology · 2024Review
- The spatiotemporal dynamics of semantic integration in the human brain.Nature communications · 2023Article
- Aberrant voxel-based degree centrality and functional connectivity in Parkinson's disease patients with fatigue.CNS neuroscience & therapeutics · 2023Article
- Neural similarity between overlapping events at learning differentially affects reinstatement across the cortex.NeuroImage · 2023Article
- Attention-Guided Autoencoder for Automated Progression Prediction of Subjective Cognitive Decline With Structural MRI.IEEE journal of biomedical and health informatics · 2023Article
- Regional Precuneus Cortical Hyperexcitability in Alzheimer's Disease Patients.Annals of neurology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Complex memory of personal events is thought to depend on coordinated reinstatement of cortical representations by the medial temporal lobes (MTL). MTL-cortical theta and gamma coupling is believed to mediate such coordination, but which cortical structures are critical for retrieval and how they influence oscillatory coupling is unclear. We used magnetoencephalography (MEG) combined with continuous theta burst stimulation (cTBS) to (i) clarify the roles of theta and gamma oscillations in network-wide communication during naturalistic memory retrieval, and (ii) understand the causal relationship between cortical network nodes and oscillatory communication. Retrieval was associated with MTL-posterior neocortical theta phase coupling and theta-gamma phase-amplitude coupling relative to a rest period. Precuneus cTBS altered MTL-neocortical communication by modulating theta and gamma oscillatory coupling. These findings provide a mechanistic account for MTL-cortical communication and demonstrate that the precuneus is a critical cortical node of oscillatory activity, coordinating cross-regional interactions that drive remembering.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.