Evidence map›Paper›PMID 30741074›Full record

Trial reportJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2020

Correlations between dopaminergic dysfunction and abnormal metabolic network activity in REM sleep behavior disorder.

Zhemin Huang, Chengfeng Jiang, Ling Li, Qian Xu, Jingjie Ge, Ming Li, Yihui Guan, Jianjun Wu, Jian Wang, Chuantao Zuo and 2 more

Open access · bronzeAbstract readClinical Trial
In one paragraph

Trial report in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Cross-modality PET image synthesis for Parkinson's Disease diagnosis: a leap from [European journal of nuclear medicine and molecular imaging · 2025
    Article
  5. Article
  6. Clinical features, disease progression, and nuclear imaging in ATXN2-related parkinsonism in a longitudinal cohort.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Functional Brain Networks to Evaluate Treatment Responses in Parkinson's Disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Predictors of RBD progression and conversion to synucleinopathies.Current neurology and neuroscience reports · 2022
    Review
  17. Review
  18. Review
  19. Neurochemical Features of Rem Sleep Behaviour Disorder.Journal of personalized medicine · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Zhemin HuangPET Center, Department of Nuclear Medicine, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.ORCID 0000-0001-5979-5037
Chengfeng JiangDepartment of Nuclear Medicine, Affiliated Kunshan Hospital, Jiangsu University, Kunshan, Jiangsu, China.
Ling LiPET Center, Department of Nuclear Medicine, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Qian XuPET Center, Department of Nuclear Medicine, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Jingjie GePET Center, Department of Nuclear Medicine, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Ming LiPET Center, Department of Nuclear Medicine, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Yihui GuanPET Center, Department of Nuclear Medicine, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Jianjun WuDepartment of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Jian WangDepartment of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Chuantao ZuoPET Center, Department of Nuclear Medicine, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Huan YuDepartment of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Ping WuPET Center, Department of Nuclear Medicine, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.ORCID 0000-0002-2758-1218
Fudan University · CNJiangsu University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Striatal dopamine transporter (DAT) deficiency and abnormal expression of Parkinson's disease (PD)-related pattern (PDRP) have been observed in patients with idiopathic REM sleep behavior disorder (IRBD). This study aimed to investigate the correlations between these two measures with comparison to PD using a dual tracer imaging design. Age-matched 37 IRBD patients, 86 PD patients, and 15 control subjects underwent concurrent PET scans with

Indexed as

Corpus StriatumPositron-Emission TomographyREM Sleep Behavior DisorderAgedDopamineDopamine Plasma Membrane Transport ProteinsFemaleFluorodeoxyglucose F18HumansMaleMiddle AgedParkinson DiseaseTropanes2beta-carbomethoxy-3beta-(4-(11C)fluorophenyl)tropaneDopamineDopamine Plasma Membrane Transport ProteinsFluorodeoxyglucose F18TropanesDopamine transportermetabolic brain networkParkinson's diseasepositron emission tomographyrapid-eye-movement sleep behavior disorder

Identifiers

PMID30741074
PMCPMC7026846
OpenAlexW2911984911

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.